An extended phase Ib study of epertinib, an orally active reversible dual EGFR/HER2 tyrosine kinase inhibitor, in patients with solid tumours.

Authors: H-T Arkenau, A Italiano, G Mak, M Toulmonde, RD Baird, J Garcia-Corbacho, R...
E-pub date: 1 Nov 2018
Journal name: Eur J Cancer

Transcription-factor-mediated supervision of global genome architecture maintains B cell identity.

Authors: TM Johanson, ATL Lun, HD Coughlan, T Tan, GK Smyth, SL Nutt, RS Allan
E-pub date: 1 Nov 2018
Journal name: Nat Immunol

Measurement of plasma cell-free mitochondrial tumor DNA improves detection of glioblastoma in patient-derived orthotopic xenograft models.

Authors: R Mair, F Mouliere, CG Smith, D Chandrananda, D Gale, F Marass, DWY Tsui, C...
Research group: Brindle Group, Rosenfeld Group
E-pub date: 31 Oct 2018
Journal name: Cancer Res

Enhanced detection of circulating tumor DNA by fragment size analysis.

Authors: F Mouliere, D Chandrananda, AM Piskorz, EK Moore, J Morris, LB Ahlborn, R M...
Research group: Brenton Group, Brindle Group, Rosenfeld Group
E-pub date: 31 Oct 2018
Journal name: Sci Transl Med

Detection of cell-free DNA fragmentation and copy number alterations in cerebrospinal fluid from glioma patients.

Authors: F Mouliere, R Mair, D Chandrananda, F Marass, CG Smith, J Su, J Morris, C W...
Research group: Brindle Group, Rosenfeld Group
E-pub date: 31 Oct 2018
Journal name: EMBO Mol Med

An adherent tissue-inspired hydrogel delivery vehicle utilised in primary human glioma models.

Authors: MJ Rowland, CC Parkins, JH McAbee, AK Kolb, R Hein, XJ Loh, C Watts, OA Sch...
E-pub date: 1 Oct 2018
Journal name: Biomaterials

Bimodal reflectance and fluorescence multispectral endoscopy based on spectrally resolving detector arrays.

Authors: AS Luthman, DJ Waterhouse, L Ansel-Bollepalli, J Yoon, GSD Gordon, J Joseph...
Research group: VISION Lab
E-pub date: 1 Oct 2018
Journal name: J Biomed Opt

Targeting Mitochondrial Metabolism in Neuroinflammation: Towards a Therapy for Progressive Multiple Sclerosis.

Authors: L Peruzzotti-Jametti, S Pluchino
E-pub date: 1 Oct 2018
Journal name: Trends Mol Med

Ischemic preconditioning protects against cardiac ischemia reperfusion injury without affecting succinate accumulation or oxidation.

Authors: VR Pell, A-M Spiroski, J Mulvey, N Burger, ASH Costa, A Logan, AV Gruszczyk...
E-pub date: 1 Oct 2018
Journal name: J Mol Cell Cardiol

Human visceral nociception: findings from translational studies in human tissue.

Authors: JRF Hockley, ESJ Smith, DC Bulmer
E-pub date: 30 Sep 2018
Journal name: Am J Physiol Gastrointest Liver Physiol

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