Transcript Identification Using Arrayed Hydrogels With TrapFISH (Adv. Mater. Technol. 18/2025)

Abstract:

Single‐cell Transcript Quantification On the cover, an artistic rendering highlights single‐cell transcript quantification using microfluidic traps. In their Research Article (10.1002/admt.202401953), Tuomas P. J. Knowles and co‐workers introduce, trapFISH, a method where individual cells are encapsulated in hydrogel beads, arrayed in microfluidic traps, and analyzed for transcript abundance through fluorescent hybridization and enzyme‐free signal amplification. Original artwork by David B. Morse.

Authors:

DB Morse, Z Toprakcioglu, A Denduluri‐Marthi, JD Brenton, CJ Thomas, TPJ Knowles

Journal:

Advanced Materials Technologies

Citation info:

10(18)

Publication date:

1st Sep 2025

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