Genomics Core Facility

We provide access to state-of-the-art DNA and RNA analysis instruments, methods and applications, and in particular next-generation sequencing.

Services: Illumina sequencing

The Genomics Core provides access to the latest Illumina next-generation sequencing (NGS) technologies. These allow unbiased genome-wide experiments to be performed that enable researchers to see, at base-pair resolution, what the underlying sequence differences are in cancer genomes. The core also provides library preparation services for genomes, exomes, transcriptomes and ChIP-seq experiments. 

We offer a variety of genomic services full-service (where we do the work) and some that are self-service (where you get access to equipment and/or reagents and/or consumables but do the work yourself).

Services: Single-cell

Single-cell library preparation service is available with 10X Genomics or Fludigm C1 platforms or with plate-based methods using nanoliter volume liquid handling robot (TTP Mosquito HV)

Services: booking other equipment

Other laboratory equipment in the core is available for trained users and requires booking through PPMS booking system.

  • Real-Time PCR systems with 384-well plate setup (2x QuantStudio 6)
    • consumables and some reagents provided in the core, sign out in PPMS
  • Agilent 4200 TapeStation for automated high-throughput DNA and RNA electrophoresis of up to 96 samples
    • reagents provided in the core, sign out in PPMS
  • Agilent 2100 Bioanalyzer (2x) for automated DNA and RNA electrophoresis and protein analysis
    • reagents provided in the core, sign out in PPMS
  • Covaris S220 ultrasonicator for DNA, RNA or chromatin shearing, tissue homogenization or cell lysis
  • Covaris LE220 high-throughput ultrasonicator for DNA, RNA or chromatin shearing, tissue homogenization or cell lysis, for up to 96 samples
  • Fluidigm Access Array for amplicon-based library preparation
  • Fluidigm Biomark HD: high-throughput microfluidic system for single-cell gene expression analysis, digital PCR, and amplicon-based target enrichment
  • Agilent Bravo Liquid Handling robot used by the core staff for library preparation and qPCR setup

If you have any questions please email our Helpdesk or see Contact us.