Senior Research Associate

Research Group Home Page: 

Work address: 
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE
Publications: 

BET inhibition as a rational therapeutic strategy for invasive lobular breast cancer.

E-pub date: 31 Jul 2019


EN1 is a transcriptional dependency in triple-negative breast cancer associated with brain metastasis.

E-pub date: 31 May 2019


Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups.

E-pub date: 28 Feb 2019


SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis.

E-pub date: 31 Jul 2018


MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models.

E-pub date: 31 Jul 2018


Shallow whole genome sequencing for robust copy number profiling of formalin-fixed paraffin-embedded breast cancers.

E-pub date: 01 Jun 2018


Dynamics of multiple resistance mechanisms in plasma DNA during EGFR-targeted therapies in non-small cell lung cancer.

E-pub date: 01 Jun 2018


Associations between genomic stratification of breast cancer and centrally reviewed tumour pathology in the METABRIC cohort.

E-pub date: 07 Mar 2018


A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.

E-pub date: 22 Sep 2016


The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes.

E-pub date: 10 May 2016


Progesterone receptor modulates ERα action in breast cancer.

E-pub date: 16 Jul 2015


A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer.

E-pub date: 31 Jan 2015


BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells.

E-pub date: 09 Jan 2015


Genome-driven integrated classification of breast cancer validated in over 7,500 samples.

E-pub date: 28 Aug 2014


JARID1B is a luminal lineage-driving oncogene in breast cancer.

E-pub date: 16 Jun 2014


Finding common regions of alteration in copy number data.

E-pub date: 31 Aug 2013


Analysis of circulating tumor DNA to monitor metastatic breast cancer.

E-pub date: 28 Mar 2013


A new genome-driven integrated classification of breast cancer and its implications.

E-pub date: 06 Mar 2013


Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor.

E-pub date: 21 Feb 2013


TGFβ induces the formation of tumour-initiating cells in claudinlow breast cancer.

E-pub date: 31 Aug 2012


The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups.

E-pub date: 18 Apr 2012


The clonal and mutational evolution spectrum of primary triple-negative breast cancers.

E-pub date: 04 Apr 2012


Detection of recurrent copy number alterations in the genome: taking among-subject heterogeneity seriously.

E-pub date: 31 Aug 2009


RJaCGH: Bayesian analysis of aCGH arrays for detecting copy number changes and recurrent regions.

E-pub date: 31 Jul 2009


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