Senior Research Associate

Research Group Home Page: 

Work address: 
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE

NRG1 fusions in breast cancer.

E-pub date: 31 Dec 2020

The molecular landscape of Asian breast cancers reveals clinically relevant population-specific differences.

E-pub date: 30 Nov 2020

Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer

E-pub date: 01 Sep 2020

Landscape of G-quadruplex DNA structural regions in breast cancer.

E-pub date: 31 Jul 2020

DNA copy number motifs are strong and independent predictors of survival in breast cancer.

E-pub date: 31 Mar 2020

Imaging mass cytometry and multiplatform genomics define the phenogenomic landscape of breast cancer

E-pub date: 01 Feb 2020

BET inhibition as a rational therapeutic strategy for invasive lobular breast cancer.

E-pub date: 31 Jul 2019

EN1 is a transcriptional dependency in triple-negative breast cancer associated with brain metastasis.

E-pub date: 31 May 2019

Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups.

E-pub date: 28 Feb 2019

SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis.

E-pub date: 31 Jul 2018

MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models.

E-pub date: 31 Jul 2018

Shallow whole genome sequencing for robust copy number profiling of formalin-fixed paraffin-embedded breast cancers.

E-pub date: 01 Jun 2018

Dynamics of multiple resistance mechanisms in plasma DNA during EGFR-targeted therapies in non-small cell lung cancer.

E-pub date: 01 Jun 2018

Associations between genomic stratification of breast cancer and centrally reviewed tumour pathology in the METABRIC cohort.

E-pub date: 07 Mar 2018

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.

E-pub date: 22 Sep 2016

The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes.

E-pub date: 10 May 2016

Progesterone receptor modulates ERα action in breast cancer.

E-pub date: 16 Jul 2015

A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer.

E-pub date: 31 Jan 2015

BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells.

E-pub date: 09 Jan 2015

Genome-driven integrated classification of breast cancer validated in over 7,500 samples.

E-pub date: 28 Aug 2014

JARID1B is a luminal lineage-driving oncogene in breast cancer.

E-pub date: 16 Jun 2014

Finding common regions of alteration in copy number data.

E-pub date: 31 Aug 2013

Analysis of circulating tumor DNA to monitor metastatic breast cancer.

E-pub date: 28 Mar 2013

A new genome-driven integrated classification of breast cancer and its implications.

E-pub date: 06 Mar 2013

Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor.

E-pub date: 21 Feb 2013

A Bayesian HMM with random effects and an unknown number of states for DNA copy number analysis

E-pub date: 31 Dec 2012

A tumor DNA complexity index is an independent predictor of survival in a dataset of 1950 breast cancers; a METABRIC group study.

E-pub date: 30 Nov 2012

Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling (Science Translational Medicine (2012) 4, (161er6))

E-pub date: 31 Oct 2012

TGFβ induces the formation of tumour-initiating cells in claudinlow breast cancer.

E-pub date: 31 Aug 2012

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups.

E-pub date: 18 Apr 2012

The clonal and mutational evolution spectrum of primary triple-negative breast cancers.

E-pub date: 04 Apr 2012

Detection of recurrent copy number alterations in the genome: taking among-subject heterogeneity seriously.

E-pub date: 31 Aug 2009

RJaCGH: Bayesian analysis of aCGH arrays for detecting copy number changes and recurrent regions.

E-pub date: 31 Jul 2009

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