Senior Research Associate

Research Group Home Page: 

Work address: 
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE
Publications: 

Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response.

E-pub date: 28 Feb 2021


NRG1 fusions in breast cancer.

E-pub date: 31 Dec 2020


The molecular landscape of Asian breast cancers reveals clinically relevant population-specific differences.

E-pub date: 30 Nov 2020


Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer

E-pub date: 01 Sep 2020


Three-Dimensional Printed Molds for Image-Guided Surgical Biopsies: An Open Source Computational Platform.

E-pub date: 31 Aug 2020


Landscape of G-quadruplex DNA structural regions in breast cancer.

E-pub date: 31 Jul 2020


Integrative radiogenomics for virtual biopsy and treatment monitoring in ovarian cancer.

E-pub date: 31 Jul 2020


Tissue-specific and interpretable sub-segmentation of whole tumour burden on CT images by unsupervised fuzzy clustering.

E-pub date: 01 May 2020


DNA copy number motifs are strong and independent predictors of survival in breast cancer.

E-pub date: 31 Mar 2020


Imaging mass cytometry and multiplatform genomics define the phenogenomic landscape of breast cancer

E-pub date: 01 Feb 2020


BET inhibition as a rational therapeutic strategy for invasive lobular breast cancer.

E-pub date: 31 Jul 2019


EN1 is a transcriptional dependency in triple-negative breast cancer associated with brain metastasis.

E-pub date: 31 May 2019


3D-printed moulds of renal tumours for image-guided tissue sampling in the clinical setting

E-pub date: 31 May 2019


Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups.

E-pub date: 28 Feb 2019


SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis.

E-pub date: 31 Jul 2018


MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models.

E-pub date: 31 Jul 2018


Shallow whole genome sequencing for robust copy number profiling of formalin-fixed paraffin-embedded breast cancers.

E-pub date: 01 Jun 2018


Dynamics of multiple resistance mechanisms in plasma DNA during EGFR-targeted therapies in non-small cell lung cancer.

E-pub date: 01 Jun 2018


Technical Note: Extension of CERR for computational radiomics: A comprehensive MATLAB platform for reproducible radiomics research.

E-pub date: 31 May 2018


Predicting hypoxia status using a combination of contrast-enhanced computed tomography and [18F]-Fluorodeoxyglucose positron emission tomography radiomics features.

E-pub date: 01 Apr 2018


Associations between genomic stratification of breast cancer and centrally reviewed tumour pathology in the METABRIC cohort.

E-pub date: 07 Mar 2018


Combined FDG and CT Radiomics Features Predict FMISO Uptake in Head and Neck Cancer

E-pub date: 30 Sep 2017


PO-0890: PET-based radiobiological modeling of changes in tumor hypoxia during chemoradiotherapy

E-pub date: 01 May 2017


A radiobiological model of radiotherapy response and its correlation with prognostic imaging variables.

E-pub date: 31 Mar 2017


A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.

E-pub date: 22 Sep 2016


High Jet Multiplicity Physics at the LHC

E-pub date: 01 Aug 2016


WE-AB-202-11: Radiobiological Modeling of Tumor Response During Radiotherapy Based On Pre-Treatment Dynamic PET Imaging Data.

E-pub date: 01 Jun 2016


Search for new phenomena in final states with large jet multiplicities and missing transverse momentum with ATLAS using √s=13 TeV proton–proton collisions

E-pub date: 31 May 2016


The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes.

E-pub date: 10 May 2016


Measurement of four-jet differential cross sections in √s=8 TeV proton-proton collisions using the ATLAS detector

E-pub date: 30 Nov 2015


Summary of the ATLAS experiment’s sensitivity to supersymmetry after LHC Run 1 — interpreted in the phenomenological MSSM

E-pub date: 30 Sep 2015


Progesterone receptor modulates ERα action in breast cancer.

E-pub date: 16 Jul 2015


A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer.

E-pub date: 31 Jan 2015


BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells.

E-pub date: 09 Jan 2015


Genome-driven integrated classification of breast cancer validated in over 7,500 samples.

E-pub date: 28 Aug 2014


JARID1B is a luminal lineage-driving oncogene in breast cancer.

E-pub date: 16 Jun 2014


Search for new phenomena in final states with large jet multiplicities and missing transverse momentum at √s = 8 TeV proton-proton collisions using the ATLAS experiment

E-pub date: 30 Sep 2013


Finding common regions of alteration in copy number data.

E-pub date: 31 Aug 2013


Analysis of circulating tumor DNA to monitor metastatic breast cancer.

E-pub date: 28 Mar 2013


A new genome-driven integrated classification of breast cancer and its implications.

E-pub date: 06 Mar 2013


Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor.

E-pub date: 21 Feb 2013


A Bayesian HMM with random effects and an unknown number of states for DNA copy number analysis

E-pub date: 31 Dec 2012


A tumor DNA complexity index is an independent predictor of survival in a dataset of 1950 breast cancers; a METABRIC group study.

E-pub date: 30 Nov 2012


Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling (Science Translational Medicine (2012) 4, (161er6))

E-pub date: 31 Oct 2012


TGFβ induces the formation of tumour-initiating cells in claudinlow breast cancer.

E-pub date: 31 Aug 2012


The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups.

E-pub date: 18 Apr 2012


The clonal and mutational evolution spectrum of primary triple-negative breast cancers.

E-pub date: 04 Apr 2012


Toward early-warning detection of gravitational waves from compact binary coalescence

E-pub date: 31 Mar 2012


Depth-dose distribution of proton beams using inelastic-collision cross sections of liquid water

E-pub date: 31 Dec 2010


Detection of recurrent copy number alterations in the genome: taking among-subject heterogeneity seriously.

E-pub date: 31 Aug 2009


RJaCGH: Bayesian analysis of aCGH arrays for detecting copy number changes and recurrent regions.

E-pub date: 31 Jul 2009


Triage-driven diagnosis for early detection of esophageal cancer using deep learning

E-pub date: 01 Jan 1970


Integrated Multi-Tumor Radio-Genomic Marker of Outcomes in Patients with High Serous Ovarian Carcinoma

E-pub date: 01 Jan 1970


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