Visiting Scientist

Research Group Home Page: 

Work address: 
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE

An activatable cancer-targeted hydrogen peroxide probe for photoacoustic and fluorescence imaging.

E-pub date: 31 Jul 2019

Genetic interactions of G-quadruplexes in humans.

E-pub date: 30 Jun 2019

DNA G-quadruplex structures mold the DNA methylome.

E-pub date: 30 Sep 2018

Unraveling Mechanisms of Chiral Induction in Double-Helical Metallopolymers.

E-pub date: 31 Jul 2018

Machine learning model for sequence-driven DNA G-quadruplex formation.

E-pub date: 06 Nov 2017

DNA G-quadruplexes in the human genome: detection, functions and therapeutic potential.

E-pub date: 31 May 2017

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.

E-pub date: 17 Feb 2017

Proximity-Induced H-Aggregation of Cyanine Dyes on DNA-Duplexes.

E-pub date: 22 Dec 2016

G-quadruplex structures mark human regulatory chromatin.

E-pub date: 31 Oct 2016

High-throughput sequencing of DNA G-quadruplex structures in the human genome.

E-pub date: 31 Aug 2015

G-quadruplex ligands exhibit differential G-tetrad selectivity.

E-pub date: 11 May 2015

Dual binding of an antibody and a small molecule increases the stability of TERRA G-quadruplex.

E-pub date: 12 Jan 2015

Dual Binding of an Antibody and a Small Molecule Increases the Stability of TERRA G-Quadruplex.

E-pub date: 12 Jan 2015

Reprogramming the mechanism of action of chlorambucil by coupling to a G-quadruplex ligand.

E-pub date: 23 Apr 2014

Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells.

E-pub date: 31 Jan 2014

Light-mediated in cell downregulation of G-quadruplex-containing genes using a photo-caged ligand.

E-pub date: 04 Oct 2013

G-quadruplex DNA as a molecular target for induced synthetic lethality in cancer cells.

E-pub date: 03 Jul 2013

Downregulation of androgen receptor transcription by promoter g-quadruplex stabilization as a potential alternative treatment for castrate-resistant prostate cancer.

E-pub date: 26 Feb 2013

An acetylene-bridged 6,8-purine dimer as a fluorescent switch-on probe for parallel G-quadruplexes.

E-pub date: 28 Jan 2013

Selective RNA versus DNA G-quadruplex targeting by in situ click chemistry.

E-pub date: 29 Oct 2012

Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells.

E-pub date: 28 Aug 2012

Experimental approaches to identify cellular G-quadruplex structures and functions.

E-pub date: 31 May 2012

Hybrid ligand-alkylating agents targeting telomeric G-quadruplex structures.

E-pub date: 14 Apr 2012

Naphthalene diimide scaffolds with dual reversible and covalent interaction properties towards G-quadruplex.

E-pub date: 31 Aug 2011

Quinone methide generation via photoinduced electron transfer.

E-pub date: 06 May 2011

Photogeneration and reactivity of naphthoquinone methides as purine selective DNA alkylating agents.

E-pub date: 20 Oct 2010

Substituted heterocyclic naphthalene diimides with unexpected acidity. Synthesis, properties, and reactivity.

E-pub date: 20 Nov 2009

Quinone methides tethered to naphthalene diimides as selective G-quadruplex alkylating agents.

E-pub date: 16 Sep 2009

Novel naphthalene diimides as activatable precursors of bisalkylating agents, by reduction and base catalysis.

E-pub date: 26 Oct 2007

Show all