Proteases and the tumour microenvironment

Active at CRUK CI: 2007-2013
Current position: Retired; Emeritus Group Leader at CRUK CI

The Murphy Group studied cell surface proteinases that modulate both the extracellular matrix and the activities of key cytokines and growth factors and have generated information on their structure-function relationships that are key to the understanding of their role in biology and pathology and the design of novel therapeutic approaches to cancer.