M Hoare, M Narita
Journal name: 
Nat Cell Biol
Citation info: 
Senescence, a cell-autonomous tumour suppressor mechanism, also has pro-tumorigenic effects on neighbouring pre-malignant cells through the senescence-associated secretory phenotype (SASP). The SASP is now shown to be regulated by inflammasomes and to induce paracrine senescence in healthy cells, indicating that senescence may also represent a non-cell-autonomous tumour suppressor mechanism linked to innate immunity.
Research group: 
Narita Group
E-pub date: 
31 Aug 2013
Users with this publication listed: 
Masashi Narita
Matthew Hoare