Authors:
K Tomimatsu, M Narita
Journal name: 
Nat Cell Biol
Citation info: 
17(10):1230-1232
Abstract: 
Cellular senescence is often accompanied by the production of secreted proteins that mediate the diverse effects of senescence on the tissue microenvironment. The mammalian target of rapamycin (mTOR), a master regulator of protein synthesis, is now shown to control the senescence-associated secretory phenotype by modulating gene transcription and mRNA translation and stabilization.
DOI: 
http://doi.org/10.1038/ncb3244
Research group: 
Narita Group
E-pub date: 
31 Oct 2015