Authors:
SJ Johnston, JS Carroll
Journal name: 
Biochim Biophys Acta
Citation info: 
1855(2):183-192
Abstract: 
Targeting the factors that regulate gene transcription is a compelling strategy in cancer therapeutics. Traditionally, these have been considered intractable targets, but recent work has revealed novel strategies for the regulation of transcription factor activity in cancer. This review will highlight some of the emerging concepts and provide examples where agents that target transcription factors are being exploited clinically for cancer therapies.
DOI: 
http://doi.org/10.1016/j.bbcan.2015.02.002
Research group: 
Carroll Group
E-pub date: 
01 Apr 2015