AJ Wills, Y Krishnan-Ghosh, S Balasubramanian
Journal name: 
J Org Chem
Citation info: 
An expedient synthesis of the polymer-supported aldehyde 3, as a Garner aldehyde equivalent, is described. Oxazolidine 3 may be obtained through preformation of aldehyde linker 4 in solution and loaded onto amine-terminating resin under peptide-coupling conditions, or alternatively via oxidation of polymer-bound alcohol 14. The integrity of the serine-derived stereocenter is maintained through all steps of the synthesis.
Research group: 
Balasubramanian Group
E-pub date: 
31 Aug 2002
Users with this publication listed: 
Shankar Balasubramanian