Authors:
RJ Simpson, KM Brindle, FF Brown, ID Campbell, DL Foxall
Journal name: 
Biochem J
Citation info: 
202(3):581-587
Abstract: 
Lactate dehydrogenase in intact erythrocytes was studied by observing isotope exchange between lactate and pyruvate by p.m.r. The inhibition of the enzyme in intact cells by both oxalate and pyruvate was found to be similar to that of the purified enzyme. The activity of the enzyme in intact cells indicates that the free solution NAD+ + NADH concentration in erythrocytes is about 10 microM whereas the total extractable NAD+ + NADH is about 80 nmol/ml of cell water.
DOI: 
http://doi.org/10.1042/bj2020581
Research group: 
Brindle Group
E-pub date: 
28 Feb 1982
Users with this publication listed: 
Kevin Brindle