Authors:
HB Lee, S Balasubramanian
Journal name: 
Org Lett
Citation info: 
2(3):323-326
Abstract: 
[reaction: see text] The solid-phase synthesis of N-alkyl-beta-keto)amides and 1,2,4,5-tetrasubstituted imidazoles was demonstrated using a traceless cleavage strategy based on benzylic acylammonium chloride reactivity. The approach enables the assembly of diverse compounds in a minimal number of steps in moderate to excellent yield (23-88%) and high purity (64-100%).
DOI: 
http://doi.org/10.1021/ol991271l
Research group: 
Balasubramanian Group
E-pub date: 
31 Jan 2000
Users with this publication listed: 
Shankar Balasubramanian