Authors:
M Di Antonio, G Biffi, A Mariani, E-A Raiber, R Rodriguez, S Balasubramanian
Journal name: 
Angew Chem Int Ed Engl
Citation info: 
51(44):11073-11078
Abstract: 
It all clicks into place: A potent telomere-targeting small molecule has been identified by using the copper-free 1,3-dipolar cycloaddition of a series of alkyne and azide building blocks catalyzed by a non-Watson-Crick DNA secondary structure (see picture). This method rapidly identifies, otherwise unanticipated, potent small-molecule probes to selectively target a given RNA or DNA.
DOI: 
http://doi.org/10.1002/anie.201206281
Research group: 
Balasubramanian Group
E-pub date: 
29 Oct 2012