Authors:
YF Mak, BA Ponder
Journal name: 
Curr Opin Genet Dev
Citation info: 
6(1):82-86
Abstract: 
RET mutations have been identified as the underlying cause of two congenital diseases that predominately affect tissues of neural crest origin: the MEN 2 cancer syndromes and a proportion of cases of dominantly inherited Hirschsprung disease, a disorder of gut development. This review summarizes the disease-causing mutations and our present understanding of their possible effects on RET protein function.
DOI: 
http://doi.org/10.1016/s0959-437x(96)90015-5
Research group: 
Ponder Group
E-pub date: 
01 Feb 1996
Users with this publication listed: 
Bruce Ponder