Authors:
BA Ponder, RJ Shearer, RD Pocock, J Miller, D Easton, CE Chilvers, M Dowsett, SL Jeffcoate
Journal name: 
Br J Cancer
Citation info: 
50(6):757-763
Abstract: 
Forty patients with metastatic adenocarcinoma of the prostate were evaluated for response to treatment with aminoglutethimide plus cortisone acetate. All had relapsed from or failed to respond to primary endocrine treatment with orchidectomy or stilboestrol. Nineteen patients (48%) showed subjective response, in most cases relief of bone pain. Side effects limited treatment in only 3 patients. We conclude that aminoglutethimide plus cortisone acetate is a useful addition to the treatment available for this difficult group of patients. The mechanism by which this treatment has a beneficial effect remains unclear.
DOI: 
http://doi.org/10.1038/bjc.1984.253
Research group: 
Ponder Group
E-pub date: 
01 Dec 1984
Users with this publication listed: 
Bruce Ponder