Authors:
TE Cawston, DN Noble, G Murphy, AJ Smith, C Woodley, B Hazleman
Journal name: 
Biochem J
Citation info: 
238(3):677-682
Abstract: 
A rapid method is described for the purification of human tissue inhibitor of metalloproteinases (TIMP) from plasma which involves immuno-affinity chromatography and gel filtration. The purified plasma inhibitor is immunologically identical with the TIMP previously purified from human amniotic fluid, human synovial fluid and human fibroblast culture medium. It is proposed that this inhibitor is identical with the plasma inhibitor previously named 'B1 anticollagenase', although the plasma inhibitor was shown to migrate as a gamma-serum component.
DOI: 
http://doi.org/10.1042/bj2380677
E-pub date: 
31 Aug 1986
Users with this publication listed: 
Gillian Murphy