Authors:
H Rao, AA Sawant, AA Tanpure, SG Srivatsan
Journal name: 
Chem Commun (Camb)
Citation info: 
48(4):498-500
Abstract: 
Direct incorporation of azide groups into RNA oligonucleotides by in vitro transcription reactions in the presence of a new azide-modified UTP analogue, and subsequent posttranscriptional chemical labeling of azide-modified oligoribonucleotide transcripts by click and Staudinger reactions are described. This postsynthetic labeling protocol is robust and modular, and offers an alternative access to RNA labeled with biophysical probes.
DOI: 
http://doi.org/10.1039/c1cc15659d
E-pub date: 
14 Jan 2012