Authors:
J Yoon, M Lee, K Lee, N Kim, JM Kim, J Park, H Yu, C Choi, WD Heo, Y Park
Journal name: 
Sci Rep
Citation info: 
5:13289
Abstract: 
We introduce a non-invasive approach for optogenetic regulation in biological cells through highly scattering skull tissue using wavefront shaping. The wavefront of the incident light was systematically controlled using a spatial light modulator in order to overcome multiple light-scattering in a mouse skull layer and to focus light on the target cells. We demonstrate that illumination with shaped waves enables spatiotemporal regulation of intracellular Ca(2+) level at the individual-cell level.
DOI: 
http://doi.org/10.1038/srep13289
E-pub date: 
31 Jul 2015
Users with this publication listed: 
Jonghee Yoon