Authors:
F Gergely, R Basto
Journal name: 
Genes Dev
Citation info: 
22(17):2291-2296
Abstract: 
Cells with extra centrosomes rely entirely on centrosome clustering mechanisms to assemble a bipolar spindle and to divide in a bipolar fashion. To identify the pathways involved in suppression of multipolarity, Kwon, Godinho, and colleagues (pp. 2189-2203) have set up a genome-wide screen in Drosophila S2 cells. Surprisingly, they found that efficient clustering requires a large number of proteins associated with a variety of cellular functions.
DOI: 
http://doi.org/10.1101/gad.1715208
Research group: 
Gergely Group
E-pub date: 
01 Sep 2008