Authors:
P Murat, MV Gormally, D Sanders, M Di Antonio, S Balasubramanian
Journal name: 
Chem Commun (Camb)
Citation info: 
49(76):8453-8455
Abstract: 
The use of a caged G-quadruplex ligand allows for transcriptional control of quadruplex-containing genes using UV light as an external trigger. An important oncogene, SRC, involved in the initiation and proliferation of epithelial tumours is shown to be significantly downregulated in cells treated by the caged ligand in synergy with UV light treatment.
DOI: 
http://doi.org/10.1039/c3cc44737e
Research group: 
Balasubramanian Group
E-pub date: 
04 Oct 2013