Authors:
M Lee, E Lee, J Jung, H Yu, K Kim, J Yoon, S Lee, Y Jeong, Y Park
Journal name: 
Sci Rep
Citation info: 
6:31034
Abstract: 
We present a wide-field quantitative label-free imaging of mouse brain tissue slices with sub-micrometre resolution, employing holographic microscopy and an automated scanning platform. From the measured light field images, scattering coefficients and anisotropies are quantitatively retrieved by using the modified the scattering-phase theorem, which enables access to structural information about brain tissues. As a proof of principle, we demonstrate that these scattering parameters enable us to quantitatively address structural alteration in the brain tissues of mice with Alzheimer's disease.
DOI: 
http://doi.org/10.1038/srep31034
E-pub date: 
31 Jul 2016
Users with this publication listed: 
Jonghee Yoon