Authors:

HAI Yoshihara, E Can, M Karlsson, MH Lerche, J Schwitter, A Comment

Journal name: 

Phys Chem Chem Phys

Citation info: 

18(18):12409-12413

Abstract: 

[1-(13)C]pyruvate is the most widely used hyperpolarized metabolic magnetic resonance imaging agent. Using a custom-built 7.0 T polarizer operating at 1.0 K and trityl radical-doped [1-(13)C]pyruvic acid, unextrapolated solution-state (13)C polarization greater than 60% was measured after dissolution and rapid transfer to a spectrometer magnet, demonstrating the signal enhancement attainable using optimized hardware. Slower rates of polarization under these conditions can be largely overcome with higher radical concentrations.

DOI: 

http://doi.org/10.1039/c6cp00589f

E-pub date: 

30 Apr 2016

Users with this publication listed: 

Arnaud Comment