Authors:
OM Rueda, R Diaz-Uriarte, C Caldas
Journal name: 
Methods Mol Biol
Citation info: 
973:339-353
Abstract: 
In this chapter, we review some recent methods designed for detecting recurrent copy number regions, that is, genomic regions that show evidence of being altered in a set of samples. We analyze Affymetrix SNP6 data from 87 Her2-type breast tumors from a recent study using three different methods, showing different definitions and features of common regions: studying heterogeneity in copy number profiles, refining candidates for driver oncogenes, and consolidating broad amplifications.
DOI: 
http://doi.org/10.1007/978-1-62703-281-0_21
Research group: 
Caldas Group
E-pub date: 
31 Aug 2013