Evaluation of nonenhancing tumor fraction assessed by dynamic contrast-enhanced MRI subtraction as a predictor of decrease in tumor volume in response to chemoradiotherapy in advanced cervical cancer.
L Mannelli, AJ Patterson, M Zahra, AN Priest, MJ Graves, DJ Lomas, LT Tan, R Crawford, J Brenton, E Sala
Journal name:
AJR Am J Roentgenol
Citation info:
195(2):524-527
Abstract:
OBJECTIVE: In this study, we evaluated the feasibility of using dynamic contrast-enhanced MRI (DCE-MRI) subtracted images as a predictor of a decrease in tumor volume in response to chemoradiotherapy in 13 patients with cervical cancer. CONCLUSION: This study shows that pretreatment tumor nonenhancing fraction assessed with arterial image subtraction inversely predicts the chemoradiation response in cervical cancer.
