Authors:
I Horsey, Y Krishnan-Ghosh, S Balasubramanian
Journal name: 
Chem Commun (Camb)
Citation info: 
(17):1950-1951
Abstract: 
Metal chelating iminodiacetic acid moieties were appended to abutting ends of two 9-mer oligonucleotides designed to hybridize contiguously on an 18-mer target. Chelation of 1 equivalent of Gd3+ cooperatively increases affinities of the oligonucleotides to the single stranded DNA target as evidenced by a 15 degrees C increase in Tm of the complex.
DOI: 
http://doi.org/10.1039/b206054j
Research group: 
Balasubramanian Group
E-pub date: 
31 Aug 2002
Users with this publication listed: 
Shankar Balasubramanian