Authors:

YA Wainman, AA Neves, S Stairs, H Stöckmann, H Ireland-Zecchini, KM Brindle, FJ Leeper

Journal name: 

Org Biomol Chem

Citation info: 

11(42):7297-7300

Abstract: 

We report the first account of metabolically labelling N-acetylglucosamine, in conjunction with either N-acetylgalactosamine or N-acetylmannosamine using a combination of isonitrile- and azide-based chemistries. With the appropriately labelled fluorescent probe molecules, that react with either the azido or isonitrile groups, the method enabled co-visualisation of cancer cell glycoproteins.

DOI: 

http://doi.org/10.1039/c3ob41805g

Research group: 

Brindle Group

E-pub date: 

14 Nov 2013