Authors:
C Lottaz, D Kostka, F Markowetz, R Spang
Journal name: 
Methods Mol Biol
Citation info: 
453:281-296
Abstract: 
Gene expression profiling using micro-arrays is a modern approach for molecular diagnostics. In clinical micro-array studies, researchers aim to predict disease type, survival, or treatment response using gene expression profiles. In this process, they encounter a series of obstacles and pitfalls. This chapter reviews fundamental issues from machine learning and recommends a procedure for the computational aspects of a clinical micro-array study.
DOI: 
http://doi.org/10.1007/978-1-60327-429-6_15
Research group: 
Markowetz Group
E-pub date: 
31 Aug 2008