Authors:
KN Baumann, AC Fux, J Joseph, SE Bohndiek, S Hernández-Ainsa
Journal name: 
Chem Commun (Camb)
Abstract: 
We report an active DNA construct capable of probing pH through a photoacoustic (PA) ratiometric analysis approach. Our nanoprobe enables different PA readout in tissue mimicking phantoms in the range between pH 6.8 to 7.8 at physiologically relevant sodium concentrations. Thus, it represents a promising platform to probe pH values relevant to the tumor microenvironment using PA.
DOI: 
http://doi.org/10.1039/c8cc04007a
Research group: 
VISION Lab
E-pub date: 
31 Jul 2018