Quantifying Microsatellite Mutation Rates from Intestinal Stem Cell Dynamics in Msh2-deficient Murine Epithelium.

Authors: J Christopher, A-S Thorsen, S Abujudeh, FC Lourenço, R Kemp, PK Potter, E ...
Research group: Winton Group
E-pub date: 30 Apr 2019
Journal name: Genetics

Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer.

Authors: KJ Lenos, DM Miedema, SC Lodestijn, LE Nijman, T van den Bosch, X Romero Ro...
Research group: Winton Group
E-pub date: 1 Oct 2018
Journal name: Nat Cell Biol

Itraconazole targets cell cycle heterogeneity in colorectal cancer.

Authors: SJA Buczacki, S Popova, E Biggs, C Koukorava, J Buzzelli, L Vermeulen, L Ha...
Research group: Winton Group
E-pub date: 2 Jul 2018
Journal name: J Exp Med

Phospho-regulation of ATOH1 Is Required for Plasticity of Secretory Progenitors and Tissue Regeneration.

Authors: G Tomic, E Morrissey, S Kozar, S Ben-Moshe, A Hoyle, R Azzarelli, R Kemp, C...
Research group: Winton Group
E-pub date: 30 Jun 2018
Journal name: Cell Stem Cell

Fixation and Spread of Somatic Mutations in Adult Human Colonic Epithelium.

Authors: AM Nicholson, C Olpe, A Hoyle, A-S Thorsen, T Rus, M Colombé, R Brunton-Si...
Research group: Winton Group, Tavaré Group
E-pub date: 1 Jun 2018
Journal name: Cell Stem Cell

Metaplastic Cdx2-depleted cells can be very disruptive neighbors.

Authors: FC Lourenço, DJ Winton
Research group: Winton Group
E-pub date: 5 Mar 2018
Journal name: J Exp Med

Mex3a Marks a Slowly Dividing Subpopulation of Lgr5+ Intestinal Stem Cells.

Authors: FM Barriga, E Montagni, M Mana, M Mendez-Lago, X Hernando-Momblona, M Sevil...
Research group: Winton Group
E-pub date: 1 Jun 2017
Journal name: Cell Stem Cell

Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation.

Authors: R Azzarelli, C Hurley, MK Sznurkowska, S Rulands, L Hardwick, I Gamper, F A...
Research group: Winton Group
E-pub date: 8 May 2017
Journal name: Dev Cell

Single-cell lineage tracing in the mammary gland reveals stochastic clonal dispersion of stem/progenitor cell progeny.

Authors: FM Davis, B Lloyd-Lewis, OB Harris, S Kozar, DJ Winton, L Muresan, CJ Watso...
Research group: Winton Group
E-pub date: 25 Oct 2016
Journal name: Nat Commun

Turning off the BCL-2 switch to prevent intestinal tumorigenesis.

Authors: M van der Heijden, DJ Winton, L Vermeulen
Research group: Winton Group
E-pub date: 17 May 2016
Journal name: Oncotarget

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