At CRUK Cambridge Institute, we perform world leading science which focuses on positively impacting cancer patients’ lives. In the Pre-Clinical Genome Editing team, our mission is to make meaningful advances to understand and treat cancer. We use cutting edge technologies to create authentic models of disease for study, and to gain novel biological insight.

As a Transgenics Service Manager, you will join the highly specialised Pre-Clinical Genome Editing team, and apply your expertise in Transgenics and CRISPR gene editing to the lead the generation of novel murine models. Our team has a wealth of expertise in Transgenics and CRISPR technology, its innovation and its application both in vitro and in vivo. You will lead our capability to edit complex cellular systems (eg mouse Embryonic Stem cells and mouse embryos of varying stages) and deliver key Transgenics services to the CRUK CI. You will have a passion and track record in advancing Transgenic technology. You will have proven expertise in leading a team, in project and budget management, and in working collaboratively with researchers to bring technological solutions to important biological questions.

Key Responsibilities:

You will lead our Transgenics capability by:

  • Playing a leading role in the design, execution, management and budgeting of all Transgenic projects
  • Representing our Transgenics efforts through interfacing with key stakeholders (eg Home Office Inspector, Vet, Animal Facility Head, NACWOs, Group Leaders and the wider Transgenics community)
  • Proactively horizon scan and lead on the early adoption of new Transgenic approaches
  • Collaborate with the Pre-Clinical Genome Editing team, researchers and other core facilities to drive the development of new, disruptive Transgenic technologies
  • Drawing upon your extensive expertise in Transgenics technologies, including: Embryonic Stem Cell transgenesis, Embryo transgenesis, IVF and core Transgenic services to drive the completion of projects

Minimum Requirements:

  • A relevant higher education degree or other relevant qualification
  • Demonstrable evidence of managing transgenics projects (including budgetary, resource, deliverables and team management)
  • Expertise in the diversity or Transgenic and assisted reproduction technologies
  • Mastery of CRISPR technology and advanced molecular skills
  • Ability to lead and manage a team, to form and maintain collaborations, and to develop networks.
  • Proactive and flexible, with a proven ability to perform under pressure.
  • Excellent and effective communication skills are essential to this role.

Candidates will be required to work outside of normal working hours.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check, a health assessment and a security check.

Click the ‘Apply’ button below to register an account with our recruitment system (if you have not already) and apply online.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.


The closing date for applications is 7 August 2020.


Interviews are expected to take place week commencing 3 August 2020.

Please quote reference SW23440 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

10 Jul 2020
7 Aug 2020