The CRUK CI, a department of the University of Cambridge, is one of Europe’s top cancer research institutes. We are situated on the Addenbrooke’s Biomedical Campus and are part of both the University of Cambridge School of Clinical Medicine, and the CRUK Cambridge Centre. The Institute is home to 18 research groups which cover a spectrum of research from basic experimental and computational cancer biology through translational cancer research to clinical application. The Institute’s scientific Core Facilities work in partnership with the Institute’s Research Groups and are a repository for deep technological expertise and knowledge, playing a fundamental role at the heart of the Institute’s research community.

The CIGC provides Next-Generation Sequencing (NGS) services for CRUK CI as well as the wider University and collaborative laboratories across The Cambridge Biomedical Campus.

You’ll be joining us at an exciting time as we continue to expand our genomics service encompassing ever larger scale genomics projects, and continue to develop our utilisation and innovation of sequencing technologies, library preparation methods, and single cell techniques; providing genomic data for CRUK CI and the University of Cambridge.

The role holder will assist in the provision of these services as well as carrying out research support directly. This will include the introduction of new methods and technologies to enhance the quality of research at the Institute. Daily duties will involve RNA / DNA sample quality control, single-cell sample receipt and processing, library preparation using standard kits from different suppliers, LIMS curation, and sequencing these samples on Illumina sequencers, data analysis of quality, and interaction with users of the services. The post-holder will be expected to work under their own initiative for most of their daily duties and also to troubleshoot and resolve any issues they encounter. They will be able to work with the relevant technical support teams of instrument suppliers and may escalate issues to a more senior member of the group depending on the severity of the issue. Contribution to teaching within the Institute will include training users on QC equipment in the CIGC.

It is essential the role holder interacts exceptionally well with the Genomics core team as well as working independently as required. They will produce project documentation including writing and editing reports, presenting data to the team and generating SOP’s.

The ideal applicant will have a degree in biological or biotechnological sciences and be experienced with a diversity of molecular biology techniques including PCR / qPCR, and DNA / RNA library prep for sequencing. They will be an excellent communicator and team player and bring a positive impact to the Core. It would be highly desirable for the post-holder to have experience with Illumina next-generation sequencing systems in a practical capacity. They will use their scientific knowledge, expertise and broad practical molecular biology skills to provide a truly excellent sequencing service, as well as helping the CIGC to set and maintain an excellent sequencing service.

This post may require some out of hours working and travel to national seminars/meetings.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a security check.

Vacancy 1 is permanent but QQR funded, whilst vacancy 2 is 12 months fixed term.

Click the ‘Apply’ button below to register an account with our recruitment system (if you have not already) and apply online.

The closing date for all applications is Thursday 19th May 2022 with interviews are expected to be held on 26th/27th May 2022.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including e-mail address and phone number, one of which must be your most recent line manager.

Please ensure that you outline how you match the criteria for the post and why you are applying for this role on the online application form.

Please quote reference SW31176 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.