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Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE

The ATR Inhibitor AZD6738 Synergizes with Gemcitabine In Vitro and In Vivo to Induce Pancreatic Ductal Adenocarcinoma Regression.

E-pub date: 11 Jun 2018

Mechanistic Distinctions between CHK1 and WEE1 Inhibition Guide the Scheduling of Triple Therapy with Gemcitabine.

E-pub date: 01 Jun 2018

CLIQ-BID: A method to quantify bacteria-induced damage to eukaryotic cells by automated live-imaging of bright nuclei.

E-pub date: 08 Jan 2018

Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors.

E-pub date: 13 Jul 2017

Protein kinase CK2 in breast cancer: the CK2β regulatory subunit takes center stage in epithelial plasticity.

E-pub date: 01 Sep 2015

Association of the breast cancer antiestrogen resistance protein 1 (BCAR1) and BCAR3 scaffolding proteins in cell signaling and antiestrogen resistance.

E-pub date: 11 Apr 2014

Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK.

E-pub date: 31 Aug 2013

NSP-CAS Protein Complexes: Emerging Signaling Modules in Cancer.

E-pub date: 31 May 2012

NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling.

E-pub date: 13 Nov 2011

SHEP1 partners with CasL to promote marginal zone B-cell maturation.

E-pub date: 02 Nov 2010

The SH2 domain protein Shep1 regulates the in vivo signaling function of the scaffolding protein Cas.

E-pub date: 01 Nov 2010

The SRC homology 2 domain protein Shep1 plays an important role in the penetration of olfactory sensory axons into the forebrain.

E-pub date: 29 Sep 2010

Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis.

E-pub date: 31 Mar 2008

Src kinase phosphorylates vascular endothelial-cadherin in response to vascular endothelial growth factor: identification of tyrosine 685 as the unique target site.

E-pub date: 15 Feb 2007

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