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Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE

Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain.

E-pub date: 31 Jul 2018

CHK2 sets the stage for CK1 in oocyte quality control.

E-pub date: 01 Jun 2018

Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63.

E-pub date: 01 Mar 2018

Protein aggregation of the p63 transcription factor underlies severe skin fragility in AEC syndrome.

E-pub date: 31 Dec 2017

Control mechanisms in germ cells mediated by p53 family proteins.

E-pub date: 31 Jul 2017

Apoptosis inhibitor 5 is an endogenous inhibitor of caspase-2.

E-pub date: 01 May 2017

Structural Evolution and Dynamics of the p53 Proteins.

E-pub date: 31 Mar 2017

Intrinsic aggregation propensity of the p63 and p73 TI domains correlates with p53R175H interaction and suggests further significance of aggregation events in the p53 family.

E-pub date: 01 Dec 2016

Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level.

E-pub date: 29 Feb 2016

Functional interplay between MDM2, p63/p73 and mutant p53.

E-pub date: 31 Jul 2015

Analysis of the oligomeric state and transactivation potential of TAp73α.

E-pub date: 31 Aug 2013

The Apaf-1-binding protein Aven is cleaved by Cathepsin D to unleash its anti-apoptotic potential.

E-pub date: 01 Sep 2012

Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer.

E-pub date: 31 Aug 2012

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