Senior Research Associate

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Work address: 
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE

Quantitative genetic analysis deciphers the impact of cis and trans regulation on cell-to-cell variability in protein expression levels.

E-pub date: 29 Feb 2020

Author Correction: Challenges in measuring and understanding biological noise.

E-pub date: 31 May 2019

Challenges in measuring and understanding biological noise.

E-pub date: 30 Apr 2019

Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability.

E-pub date: 30 Nov 2018

A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer.

E-pub date: 31 Aug 2018

Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens.

E-pub date: 01 Aug 2018

Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients.

E-pub date: 01 Jul 2018

Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors.

E-pub date: 01 Jun 2018

CpG island composition differences are a source of gene expression noise indicative of promoter responsiveness.

E-pub date: 31 May 2018

Myc Cooperates with Ras by Programming Inflammation and Immune Suppression.

E-pub date: 30 Nov 2017

Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer.

E-pub date: 29 Aug 2017

Correcting batch effects in single-cell RNA sequencing data by matching mutual nearest neighbours

E-pub date: 30 Jun 2017

High-fat diet disrupts metabolism in two generations of rats in a parent-of-origin specific manner.

E-pub date: 31 Jul 2016

MTHFR functional genetic variation and methotrexate treatment response in rheumatoid arthritis: a meta-analysis.

E-pub date: 01 Mar 2014

A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis.

E-pub date: 15 Oct 2013

Allele-dose association of the C5orf30 rs26232 variant with joint damage in rheumatoid arthritis.

E-pub date: 01 Oct 2013

The Myc world within reach.

E-pub date: 31 Aug 2013

Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice.

E-pub date: 01 Mar 2013

Myc – a Non Redundant Function in Cancer

E-pub date: 01 Jul 2012

Modeling Pharmacological Inhibition of Bruton’s Tyrosine Kinase (BTK) as a Therapy for Insulinoma and Pancreatic Ductal Adenocarcinoma

E-pub date: 01 Jul 2012

Finding cancer’s weakest link.

E-pub date: 31 Dec 2011

Ligand-dependent corepressor acts as a novel androgen receptor corepressor, inhibits prostate cancer growth, and is functionally inactivated by the Src protein kinase.

E-pub date: 28 Oct 2011

Differential C3NET reveals disease networks of direct physical interactions.

E-pub date: 21 Jul 2011

Reduction of pancreatic acinar cell tumor multiplicity in Dnmt1 hypomorphic mice.

E-pub date: 01 Jun 2011

Endogenous Myc maintains the tumor microenvironment.

E-pub date: 01 May 2011

Green tea polyphenol EGCG blunts androgen receptor function in prostate cancer.

E-pub date: 01 Apr 2011

Evaluation of the rheumatoid arthritis susceptibility loci HLA-DRB1, PTPN22, OLIG3/TNFAIP3, STAT4 and TRAF1/C5 in an inception cohort.

E-pub date: 01 Aug 2010

Nursing some sense out of Myc.

E-pub date: 28 Sep 2009

Modelling Myc inhibition as a cancer therapy.

E-pub date: 02 Oct 2008

Role of methionine adenosyltransferase 2A and S-adenosylmethionine in mitogen-induced growth of human colon cancer cells.

E-pub date: 31 Jul 2007

Photoprotective effects of some quinoxaline 1,4-dioxides in hairless mice.

E-pub date: 01 Dec 1998

Ageing compromises mouse thymus function and remodels epithelial cell differentiation

E-pub date: 01 Jan 1970

Ageing compromises mouse thymus function and remodels epithelial cell differentiation

E-pub date: 01 Jan 1970

Milo: differential abundance testing on single-cell data using k-NN graphs

E-pub date: 01 Jan 1970

Single-cell multi-omics analysis of the immune response in COVID-19

E-pub date: 01 Jan 1970

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