Postdoc

Research Group Home Page: 

Work address: 
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE
Publications: 

Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response.

E-pub date: 28 Feb 2021


OC-0451: Radiation response of breast carcinoma cells with enhanced metastatic capacities

E-pub date: 01 Nov 2020


Circulating tumour DNA analysis using three next generation sequencing approaches in a phase 1b trial of ER positive metastatic breast cancer

E-pub date: 30 Sep 2020


BioItaLEE: Comparative biomarker analysis of liquid biopsies and paired tissue samples of patients treated with ribociclib and letrozole as first-line therapy for advanced breast cancer (aBC)

E-pub date: 01 May 2020


Molecular heterogeneity in breast carcinoma cells with increased invasive capacities.

E-pub date: 31 Jan 2020


Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing.

E-pub date: 31 Oct 2019


POSEIDON phase 1b results: safety, efficacy and ctDNA response of taselisib combined with tamoxifen in hormone receptor positive metastatic breast cancer patients.

E-pub date: 31 Jul 2019


Correction: By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy.

E-pub date: 31 Jul 2019


Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups.

E-pub date: 28 Feb 2019


Dynamics of breast cancer relapse reveal molecularly defined late recurring ER-positive subgroups: Results from the METABRIC study

E-pub date: 01 Feb 2019


Next Generation-Targeted Amplicon Sequencing (NG-TAS): an optimised protocol and computational pipeline for cost-effective profiling of circulating tumour DNA.

E-pub date: 31 Dec 2018


Diagnostic role of circulating extracellular matrix-related proteins in non-small cell lung cancer.

E-pub date: 31 Aug 2018


Predicting and Understanding Cancer Response to Treatment.

E-pub date: 01 Aug 2018


PATRI, a Genomics Data Integration Tool for Biomarker Discovery.

E-pub date: 01 Aug 2018


PO-387 Differential gene methylation in triple negative breast cancer and non-tumoral mammary tissue

E-pub date: 01 Jul 2018


PO-386 Decoding the regulatory role and epiclonal dynamics of DNA methylation in 1482 breast tumours

E-pub date: 01 Jul 2018


Next Generation-Targeted Amplicon Sequencing (NG-TAS): An optimised protocol and computational pipeline for cost-effective profiling of circulating tumour DNA

E-pub date: 30 Jun 2018


PO-491 Single-cell phenotypic profiling of breast cancerpatient-derived tumour xenografts using mass cytometry

E-pub date: 01 Jun 2018


Computational approach to discriminate human and mouse sequences in patient-derived tumour xenografts.

E-pub date: 05 Jan 2018


Dissecting Time- from Tumor-Related Gene Expression Variability in Bilateral Breast Cancer.

E-pub date: 31 Dec 2017


Prognostic and functional role of subtype-specific tumor-stroma interaction in breast cancer.

E-pub date: 01 Oct 2017


Integrative analysis of molecular and drug response data from clinical samples and PDTXs to identify pharmacogenomic associations in breast cancer

E-pub date: 01 Jul 2017


A microenvironment gene signature predicts poor outcome in patients with luminal breast cancers subjected to local-regional treatment

E-pub date: 01 Jul 2017


Intersect-then-combine approach: improving the performance of somatic variant calling in whole exome sequencing data using multiple aligners and callers.

E-pub date: 18 Apr 2017


Involvement of AF1q/MLLT11 in the progression of ovarian cancer.

E-pub date: 31 Mar 2017


A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.

E-pub date: 22 Sep 2016


A computational approach to discriminate between human and mouse reads in sequencing data from Patient Derived Tumour Xenografts

E-pub date: 01 Jul 2016


Identifying changes in mutational dynamics in patients with early breast cancer undergoing neoadjuvant chemotherapy

E-pub date: 01 Jul 2016


Dynamics of relapse in breast cancer

E-pub date: 01 Jul 2016


Cancer-associated fibroblasts transcriptional pattern reveals common changes in extracellular matrix-related genes across different cancer types

E-pub date: 01 Jul 2016


Comprehensive sequencing-based characterisation of the DNA methylation landscape of 1300 breast tumours

E-pub date: 01 Jul 2016


In-depth characterization of breast cancer tumor-promoting cell transcriptome by RNA sequencing and microarrays.

E-pub date: 31 Dec 2015


Subtype-Specific Metagene-Based Prediction of Outcome after Neoadjuvant and Adjuvant Treatment in Breast Cancer.

E-pub date: 31 Dec 2015


Complexity in the tumour microenvironment: Cancer associated fibroblast gene expression patterns identify both common and unique features of tumour-stroma crosstalk across cancer types.

E-pub date: 31 Dec 2015


Proposal of supervised data analysis strategy of plasma miRNAs from hybridisation array data with an application to assess hemolysis-related deregulation.

E-pub date: 31 Oct 2015


Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation.

E-pub date: 30 Sep 2015


Challenges in using circulating miRNAs as cancer biomarkers.

E-pub date: 01 Aug 2015


Use of formalin-fixed paraffin-embedded samples for gene expression studies in breast cancer patients.

E-pub date: 01 Aug 2015


Molecular portrait of breast cancer in China reveals comprehensive transcriptomic likeness to Caucasian breast cancer and low prevalence of luminal A subtype.

E-pub date: 01 Jul 2015


miR-30e* is an independent subtype-specific prognostic marker in breast cancer.

E-pub date: 30 Jun 2015


Circulating Biomarkers for Prediction of Treatment Response.

E-pub date: 01 May 2015


Contribution of immune system and tumor-related interferon signaling to epirubicin response in triple-negative (TN) breast cancers.

E-pub date: 30 Apr 2015


The heterogeneous clinical behavior of luminal breast cancers is associated with different mutational landscapes

E-pub date: 30 Apr 2015


By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy.

E-pub date: 31 Jan 2015


Gene expression profiling of circulating tumor cells in breast cancer.

E-pub date: 01 Jan 2015


Subtype-dependent prognostic relevance of an interferon-induced pathway metagene in node-negative breast cancer.

E-pub date: 01 Oct 2014


Accurate data processing improves the reliability of Affymetrix gene expression profiles from FFPE samples.

E-pub date: 01 Aug 2014


A lipemia-independent NanoDrop(®)-based score to identify hemolysis in plasma and serum samples.

E-pub date: 01 May 2014


An immune-related signature for prediction of risk of late recurrences beyond proliferation and ER-related genes in ER-positive breast cancer.

E-pub date: 30 Apr 2014


Erratum: Accurate data processing improves the reliability of affymetrix gene expression profiles from FFPE samples (PLoS ONE (2014) 9:1 (e86511))

E-pub date: 31 Mar 2014


Accurate Data Processing Improves the Reliability of Affymetrix Gene Expression Profiles from FFPE Samples (vol 9, e86511, 2014)

E-pub date: 31 Mar 2014


Mesenchymal to amoeboid transition is associated with stem-like features of melanoma cells.

E-pub date: 31 Mar 2014


miR-205 hinders the malignant interplay between prostate cancer cells and associated fibroblasts.

E-pub date: 28 Feb 2014


Breast cancer in China reveals transcriptomic likeness to Caucasian breast cancer

E-pub date: 30 Nov 2013


Expression of immune checkpoint related genes are prognostic in untreated breast cancer

E-pub date: 30 Nov 2013


Bioinformatics tools for secretome analysis.

E-pub date: 01 Nov 2013


Measuring microRNA expression levels in oncology: from samples to data analysis.

E-pub date: 01 Aug 2013


Effects of warm ischemic time on gene expression profiling in colorectal cancer tissues and normal mucosa.

E-pub date: 01 Aug 2013


Correction: Effects of warm ischemic time on gene expression profiling in colorectal cancer tissues and normal mucosa (PLoS ONE)

E-pub date: 31 May 2013


Feasibility of circulating miRNA microarray analysis from archival plasma samples.

E-pub date: 31 May 2013


Correction: Comparison of microarray platforms for measuring differential MicroRNA expression in paired normal/cancer colon tissues (PLoS ONE)

E-pub date: 30 Apr 2013


Proliferation-, estrogen-, and T-cell-related metagenes to predict outcome after adjuvant/neoadjuvant chemotherapy for operable breast cancer in the ECTO trial.

E-pub date: 30 Apr 2013


MIR-205 puts the brakes on the malignant interplay between prostate cancer cells and associated fibroblasts

E-pub date: 31 Jan 2013


MicroRNA detection in plasma samples: how to treat heparinized plasma.

E-pub date: 01 Jan 2013


Clinical implications of molecular heterogeneity in highly proliferative, ER-positive, HER2-negative breast cancer

E-pub date: 30 Nov 2012


miR-205 regulates basement membrane deposition in human prostate: implications for cancer development.

E-pub date: 01 Nov 2012


ER + /HER2+ and ER-/Her2+ Breast Cancers are Molecularly Distinct but Immune Gene Signatures are Prognostic and Predictive in Both Groups

E-pub date: 01 Sep 2012


AF1q: a novel mediator of basal and 4-HPR-induced apoptosis in ovarian cancer cells.

E-pub date: 01 Aug 2012


Comparison of microarray platforms for measuring differential microRNA expression in paired normal/cancer colon tissues.

E-pub date: 01 Aug 2012


Improving the Reliability of Gene Expression Profiles From FFPE Samples Using Alternative Chip Description Files

E-pub date: 01 Jul 2012


Comparison of Microarray Platforms for Measuring Differential MicroRNA Expression in Paired Normal/cancer Colon Tissues

E-pub date: 01 Jul 2012


AF1q-a Novel Mediator of Basal and 4-HPR-Induced Apoptosis in Ovarian Cancer Cells

E-pub date: 01 Jul 2012


Dissecting time- from tumor-related gene expression variability in the bilateral breast cancer model

E-pub date: 01 Oct 2011


Gene expression profiling of circulating tumor cells in breast cancer

E-pub date: 01 Oct 2011


Gene expression analysis reveals a different transcriptomic landscape in female and male breast cancer.

E-pub date: 01 Jun 2011


miR-21: an oncomir on strike in prostate cancer.

E-pub date: 31 Dec 2009


Impact of biospecimens handling on biomarker research in breast cancer.

E-pub date: 31 Oct 2009


Genes associated to development of distant metastases in node negative breast cancer patients

E-pub date: 01 Oct 2009


Effect of fixative and sample age on success rate in gene profiling studies

E-pub date: 01 Oct 2009


Comparability and reliability of different approaches to obtain gene expression measurements from formalin-fixed, paraffin-embedded breast cancer samples

E-pub date: 01 Oct 2009


A transcriptional sketch of a primary human breast cancer by 454 deep sequencing.

E-pub date: 31 Mar 2009


Reciprocal regulation of p63 by C/EBP delta in human keratinocytes.

E-pub date: 31 Aug 2007


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