Advanced Clinician Scientist

Research Group Home Page: 

Work address: 
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE
Publications: 

Lipid remodelling in hepatocyte proliferation and hepatocellular carcinoma.

E-pub date: 30 Apr 2020


Somatic mutations and clonal dynamics in healthy and cirrhotic human liver.

E-pub date: 01 Oct 2019


NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence.

E-pub date: 09 May 2018


Notch and Senescence.

E-pub date: 01 Jan 2018


The Power Behind the Throne: Senescence and the Hallmarks of Cancer

E-pub date: 31 Dec 2017


Spatial and Temporal Control of Senescence.

E-pub date: 01 Nov 2017


NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence

E-pub date: 31 Oct 2017


NOTCH and the 2 SASPs of senescence.

E-pub date: 01 Feb 2017


NOTCH1 mediates a switch between two distinct secretomes during senescence.

E-pub date: 01 Sep 2016


A NOTCH1-DRIVEN SECRETOME SWITCH MODULATES IMMUNE SURVEILLANCE IN RAS-INDUCED SENESCENCE

E-pub date: 01 Jun 2016


Persistence of Hepatitis C Virus Traces after Spontaneous Resolution of Hepatitis C.

E-pub date: 31 Aug 2015


NOTCH1 IS A MASTER REGULATOR OF THE SENESCENCE SECRETOME THROUGH REPRESSION OF C/EBP

E-pub date: 01 Jun 2015


Notch1 IS A MASTER REGULATOR OF THE SENESCENCE SECRETOME THROUGH REPRESSION OF CEBP beta

E-pub date: 01 Apr 2015


IDENTIFICATION OF OPTIMAL CUT-OFFS IN ALPHA-FETOPROTEIN AND THE “AFP SCORE” TO MAXIMISE THE ACCURACY OF SELECTION OF LIVER TRANSPLANT CANDIDATES WITH HEPATOCELLULAR CARCINOMA

E-pub date: 01 Apr 2015


A retrospective 15-year review: survival advantage after switching to sirolimus in hepatitis C virus infected liver graft recipients.

E-pub date: 01 Feb 2015


Selective insulin resistance in hepatocyte senescence.

E-pub date: 01 Feb 2015


The senescent hepatocyte gene signature in chronic liver disease.

E-pub date: 31 Dec 2014


SELECTIVE SWITCHING FROM CNI-BASED IMMUNE SUPPRESSION TO SIROLIMUS IMPROVES OUTCOME AFTER LIVER TRANSPLANTATION IN PATIENTS WITH HEPATITIS C VIRUS INFECTION

E-pub date: 01 Apr 2014


Cellular senescence and its effector programs.

E-pub date: 15 Jan 2014


Transmitting senescence to the cell neighbourhood.

E-pub date: 31 Aug 2013


Hepatocyte expression of the senescence marker p21 is linked to fibrosis and an adverse liver-related outcome in alcohol-related liver disease.

E-pub date: 31 Aug 2013


Orthotopic liver transplantation in an adult with cholesterol ester storage disease.

E-pub date: 31 Aug 2013


γ-H2AX+CD8+ T lymphocytes cannot respond to IFN-α, IL-2 or IL-6 in chronic hepatitis C virus infection.

E-pub date: 31 May 2013


PLASMA MEMBRANE PROTEOMICS IDENTIFIES Notch1 AS A POTENTIAL REGULATOR OF Ras-INDUCED SENESCENCE

E-pub date: 01 Apr 2013


Replication-timing boundaries facilitate cell-type and species-specific regulation of a rearranged human chromosome in mouse.

E-pub date: 01 Oct 2012


Autophagy in cancer: having your cake and eating it.

E-pub date: 31 Dec 2011


The pattern of late mortality in liver transplant recipients in the United Kingdom.

E-pub date: 15 Jun 2011


Ageing, telomeres, senescence, and liver injury.

E-pub date: 01 Nov 2010


CD4+ T-lymphocyte telomere length is related to fibrosis stage, clinical outcome and treatment response in chronic hepatitis C virus infection.

E-pub date: 31 Aug 2010


Features of immune senescence in liver transplant recipients with established grafts.

E-pub date: 31 May 2010


Heterogeneous inflammatory changes in liver graft recipients with normal biochemistry.

E-pub date: 27 Mar 2010


Reply

E-pub date: 31 May 2009


Histological changes in HCV antibody-positive, HCV RNA-negative subjects suggest persistent virus infection.

E-pub date: 31 Dec 2008


Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection.

E-pub date: 01 Sep 2008


T-regulatory lymphocytes and chronic viral hepatitis.

E-pub date: 01 Nov 2007


Distribution of the receptor EphA7 and its ligands in development of the mouse nervous system.

E-pub date: 30 Nov 1999


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