RS & Mngr of 600MHz MR Instmnt

Research Group Home Page: 
Pre-clinical Imaging

Work address: 
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE
Publications: 

SDHC epi-mutation testing in gastrointestinal stromal tumours and related tumours in clinical practice.

E-pub date: 30 Jun 2019


The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia.

E-pub date: 03 Apr 2018


Translating in vivo metabolomic analysis of succinate dehydrogenase deficient tumours into clinical utility.

E-pub date: 28 Feb 2018


The action of β-hydroxybutyrate on the growth, metabolism and global histone H3 acetylation of spontaneous mouse mammary tumours: evidence of a β-hydroxybutyrate paradox.

E-pub date: 31 Aug 2017


Exploration of human brain tumour metabolism using pairwise metabolite-metabolite correlation analysis (MMCA) of HR-MAS 1H NMR spectra.

E-pub date: 31 Aug 2017


Special Issue: Cancer Metabolism.

E-pub date: 09 Aug 2017


Response of Degarelix treatment in human prostate cancer monitored by HR-MAS 1H NMR spectroscopy.

E-pub date: 31 Aug 2016


Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target.

E-pub date: 31 May 2016


Metabolomic changes during cellular transformation monitored by metabolite-metabolite correlation analysis and correlated with gene expression.

E-pub date: 31 Aug 2015


Artefacts in 1H NMR-based metabolomic studies on cell cultures.

E-pub date: 01 Apr 2015


Normalization of metabolomics data with applications to correlation maps.

E-pub date: 01 Aug 2014


Gemcitabine diphosphate choline is a major metabolite linked to the Kennedy pathway in pancreatic cancer models in vivo.

E-pub date: 15 Jul 2014


Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer.

E-pub date: 17 Jun 2014


Effects of perhexiline-induced fuel switch on the cardiac proteome and metabolome.

E-pub date: 01 Feb 2013


Fluorescence-guided surgical sampling of glioblastoma identifies phenotypically distinct tumour-initiating cell populations in the tumour mass and margin.

E-pub date: 24 Jul 2012


A novel method for quantification of gemcitabine and its metabolites 2′,2′-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with (19)F NMR spectroscopy.

E-pub date: 01 Nov 2011


Metabolic homeostasis is maintained in myocardial hibernation by adaptive changes in the transcriptome and proteome.

E-pub date: 01 Jun 2011


The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis.

E-pub date: 20 May 2011


Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques.

E-pub date: 31 Aug 2009


Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.

E-pub date: 12 Jun 2009


Proteomic and metabolomic analysis of cardioprotection: Interplay between protein kinase C epsilon and delta in regulating glucose metabolism of murine hearts.

E-pub date: 01 Feb 2009


Effect of Gd-DTPA-BMA on choline signals of HT29 tumors detected by in vivo 1H MRS.

E-pub date: 01 Nov 2008


Proteomic and metabolomic analysis of smooth muscle cells derived from the arterial media and adventitial progenitors of apolipoprotein E-deficient mice.

E-pub date: 09 May 2008


Combined metabolomic and proteomic analysis of human atrial fibrillation.

E-pub date: 05 Feb 2008


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