Senior Bioinformatics Analyst

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Kamal obtained his PhD at the University of Milan in the field of computational epigenomics. His PhD involved developing computational tools for integrative analysis of epigenomics data. He joined Bioinformatics core at CRUK CI in 2016. His main activities involves analysis of heterogenous genomics and proteomics data. He work in close collaboration with biologists to analytically answer challenging biological questions. The development of robust software solutions with contributions to Bioconductor project forms an integral part of the work.



ORCID: 0000-0002-8479-3110

Work address: 
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE

TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions.

E-pub date: 31 Jan 2021

C5a impairs phagosomal maturation in the neutrophil through phosphoproteomic remodelling.

E-pub date: 30 Jun 2020

Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription.

E-pub date: 30 Jun 2020

IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis.

E-pub date: 30 Jun 2020

ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response.

E-pub date: 31 Dec 2019

Ontology-driven integrative analysis of omics data through Onassis.

E-pub date: 31 Dec 2019

ZMIZ1 — A novel Estrogen Receptor co-activator that enhances the growth of ER+ breast cancer

E-pub date: 30 Sep 2019

DNA methylation dynamics during embryonic development and postnatal maturation of the mouse auditory sensory epithelium.

E-pub date: 31 Oct 2018

Identification of Differentially Methylated Regions in the Genome of Arabidopsis thaliana.

E-pub date: 01 Aug 2018

A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes.

E-pub date: 13 Jun 2018

DNA methylation variations are required for epithelial-to-mesenchymal transition induced by cancer-associated fibroblasts in prostate cancer cells.

E-pub date: 30 Sep 2017

Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours.

E-pub date: 27 Jun 2017

Integrated Systems for NGS Data Management and Analysis: Open Issues and Available Solutions.

E-pub date: 01 Aug 2016

methylPipe and compEpiTools: a suite of R packages for the integrative analysis of epigenomics data.

E-pub date: 31 Aug 2015

IL6/STAT3 co-opts ER regulatory elements to drive metastasis in breast cancer

E-pub date: 01 Jan 1970

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