Associate Scientist

Research Group Home Page: 

Work address: 
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE

Landscape of G-quadruplex DNA structural regions in breast cancer.

E-pub date: 31 Jul 2020

Genome-wide DNA methylation signatures are determined by DNMT3A/B sequence preferences.

E-pub date: 31 May 2020

The regulation and functions of DNA and RNA G-quadruplexes.

E-pub date: 31 Mar 2020

Genetic interactions of G-quadruplexes in humans.

E-pub date: 30 Jun 2019

DNA G-quadruplex structures mold the DNA methylome.

E-pub date: 30 Sep 2018

Analysis of NRAS RNA G-quadruplex binding proteins reveals DDX3X as a novel interactor of cellular G-quadruplex containing transcripts.

E-pub date: 31 Aug 2018

Identification of the extracellular matrix protein Fibulin-2 as a regulator of spinal nerve organization.

E-pub date: 31 May 2018

Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and high-throughput sequencing.

E-pub date: 31 Mar 2018

Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule.

E-pub date: 22 Mar 2018

DSBCapture: in situ capture and sequencing of DNA breaks.

E-pub date: 31 Oct 2016

G-quadruplex structures mark human regulatory chromatin.

E-pub date: 31 Oct 2016

FOXM1 binds directly to non-consensus sequences in the human genome.

E-pub date: 23 Jun 2015

Elevated levels of G-quadruplex formation in human stomach and liver cancer tissues.

E-pub date: 31 Aug 2014

Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells.

E-pub date: 31 Jan 2014

G-quadruplex structures are stable and detectable in human genomic DNA.

E-pub date: 31 Aug 2013

Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes.

E-pub date: 18 Jul 2013

G-quadruplex DNA as a molecular target for induced synthetic lethality in cancer cells.

E-pub date: 03 Jul 2013

Quantitative visualization of DNA G-quadruplex structures in human cells.

E-pub date: 31 Mar 2013

An intramolecular G-quadruplex structure is required for binding of telomeric repeat-containing RNA to the telomeric protein TRF2.

E-pub date: 25 Jul 2012

The generation of vertebral segmental patterning in the chick embryo.

E-pub date: 01 Jun 2012

The intrinsic innervation of the lung is derived from neural crest cells as shown by optical projection tomography in Wnt1-Cre;YFP reporter mice.

E-pub date: 31 Dec 2010

Mutations in FLVCR2 are associated with proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome (Fowler syndrome).

E-pub date: 12 Mar 2010

Mutations in SLC29A3, encoding an equilibrative nucleoside transporter ENT3, cause a familial histiocytosis syndrome (Faisalabad histiocytosis) and familial Rosai-Dorfman disease.

E-pub date: 05 Feb 2010

Extensive molecular differences between anterior- and posterior-half-sclerotomes underlie somite polarity and spinal nerve segmentation.

E-pub date: 22 May 2009

Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code.

E-pub date: 01 Dec 2008

Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development.

E-pub date: 06 Nov 2007

Genome-wide computational screen for bloon stem cell enhancers integrates RUNX1 and the BMP signaling pathway into the SCL transcriptional network

E-pub date: 01 Mar 2007

Molecular analysis of axon repulsion by the notochord.

E-pub date: 01 Mar 2003

A critical role for sonic hedgehog signaling in the early expansion of the developing brain

E-pub date: 01 Feb 2002

The role of the notochord in vertebral column formation

E-pub date: 31 Aug 2001

The role of the notochord in vertebral column formation.

E-pub date: 01 Jul 2001

Axon guidance and somites

E-pub date: 01 Feb 1998

Axon guidance to and from choice points.

E-pub date: 01 Feb 1998

Axon guidance and somites.

E-pub date: 01 Nov 1997

Surround repulsion of spinal sensory axons in higher vertebrate embryos.

E-pub date: 01 Jun 1997

Enlightening the path of axons.

E-pub date: 01 Dec 1996

Identification and developmental expression of the Xenopus laevis cystic fibrosis transmembrane conductance regulator gene.

E-pub date: 01 May 1992

Effects of orientation and position on the activity of a herpes simplex virus immediate early gene far-upstream region.

E-pub date: 01 Sep 1984

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