Research Group Home Page: 

Work address: 
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE
Publications: 

Radiotherapy Trial Set-up in the UK: Identifying Inefficiencies and Potential Solutions.

E-pub date: 31 Oct 2019


The SMALL Trial: A Big Change for Small Breast Cancers.

E-pub date: 01 Sep 2019


Breast Cancer Demographics, Types and Management Pathways: Can Western Algorithms be Optimally used in Eastern Countries?

E-pub date: 31 Aug 2019


The Breast Cancer Trainees Research Collaborative Group: A New Multidisciplinary Network to Facilitate Breast Cancer Research.

E-pub date: 30 Jun 2019


Axillary Surgery Following Neoadjuvant Chemotherapy – Multidisciplinary Guidance From the Association of Breast Surgery, Faculty of Clinical Oncology of the Royal College of Radiologists, UK Breast Cancer Group, National Coordinating Committee for Breast Pathology and British Society of Breast Radiology.

E-pub date: 31 May 2019


Can patient-reported outcomes be used instead of clinician-reported outcomes and photographs as primary endpoints of late normal tissue effects in breast radiotherapy trials? Results from the IMPORT LOW trial.

E-pub date: 01 May 2019


ESTRO ACROP consensus guideline for target volume delineation in the setting of postmastectomy radiation therapy after implant-based immediate reconstruction for early stage breast cancer.

E-pub date: 30 Apr 2019


Is breast seroma after tumour resection associated with patient-reported breast appearance change following radiotherapy? Results from the IMPORT HIGH (CRUK/06/003) trial.

E-pub date: 31 Mar 2019


The Assisi Think Tank Meeting Survey of post-mastectomy radiation therapy in ductal carcinoma in situ: Suggestions for routine practice.

E-pub date: 31 Mar 2019


Patient-Reported Outcomes Over 5 Years After Whole- or Partial-Breast Radiotherapy: Longitudinal Analysis of the IMPORT LOW (CRUK/06/003) Phase III Randomized Controlled Trial.

E-pub date: 31 Jan 2019


Practice-changing radiation therapy trials for the treatment of cancer: where are we 150 years after the birth of Marie Curie?

E-pub date: 31 Aug 2018


A Dosimetric Comparison of Breast Radiotherapy Techniques to Treat Locoregional Lymph Nodes Including the Internal Mammary Chain.

E-pub date: 01 Jun 2018


The Assisi Think Tank Meeting and Survey of post MAstectomy Radiation Therapy after breast reconstruction: The ATTM-SMART report.

E-pub date: 01 Apr 2018


Can Interrogation of Tumour Characteristics Lead us to Safely Omit Adjuvant Radiotherapy in Patients with Early Breast Cancer?

E-pub date: 01 Mar 2018


Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials.

E-pub date: 01 Jan 2018


Targeted radiotherapy for early breast cancer – Authors’ reply.

E-pub date: 31 Dec 2017


Preoperative breast radiation therapy: Indications and perspectives.

E-pub date: 01 Sep 2017


Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial.

E-pub date: 31 Aug 2017


Preoperative radiation therapy: The ‘new’ targeted breast cancer treatment?

E-pub date: 01 Jun 2017


Treatment of the axilla in patients with primary breast cancer and low burden axillary disease: Limitations of the evidence from randomised controlled trials.

E-pub date: 01 Feb 2017


Another piece in the jigsaw of accelerated partial breast irradiation.

E-pub date: 01 Feb 2017


Unanswered Questions Concerning Locoregional Irradiation in Breast Cancer-Reply.

E-pub date: 01 Jan 2017


Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients.

E-pub date: 31 Dec 2016


The 2016 Assisi Think Tank Meeting on breast cancer: white paper.

E-pub date: 01 Nov 2016


It’s PRIMETIME. Postoperative Avoidance of Radiotherapy: Biomarker Selection of Women at Very Low Risk of Local Recurrence.

E-pub date: 01 Sep 2016


A multicentre study of the evidence for customized margins in photon breast boost radiotherapy.

E-pub date: 31 Aug 2016


Treatment of Regional Lymph Nodes in Breast Cancer-Evidence in Favor of Radiation Therapy.

E-pub date: 01 Aug 2016


Acute skin toxicity associated with a 1-week schedule of whole breast radiotherapy compared with a standard 3-week regimen delivered in the UK FAST-Forward Trial.

E-pub date: 31 Jul 2016


The Cambridge Breast Intensity-modulated Radiotherapy Trial: Comparison of Clinician- versus Patient-reported Outcomes.

E-pub date: 01 Jun 2016


Patients with a High Polygenic Risk of Breast Cancer do not have An Increased Risk of Radiotherapy Toxicity.

E-pub date: 15 Mar 2016


Accelerated partial breast irradiation: the new standard?

E-pub date: 16 Jan 2016


Survivorship Issues in Radiation Oncology.

E-pub date: 01 Nov 2015


The Radiotherapy Clinical Trial Research Landscape in the UK Between 2004 and 2013: A Cross-sectional Analysis.

E-pub date: 01 Sep 2015


Clinical impact of IMPORT HIGH trial (CRUK/06/003) on breast radiotherapy practices in the United Kingdom.

E-pub date: 31 Aug 2015


XRCC1 Polymorphism Associated With Late Toxicity After Radiation Therapy in Breast Cancer Patients.

E-pub date: 01 Aug 2015


Recommendations for standardized pathological characterization of residual disease for neoadjuvant clinical trials of breast cancer by the BIG-NABCG collaboration.

E-pub date: 31 Jul 2015


The IMPORT HIGH image-guided radiotherapy study: a model for assessing image-guided radiotherapy.

E-pub date: 31 Jan 2015


The effect of image guidance on dose distributions in breast boost radiotherapy.

E-pub date: 01 Nov 2014


What is the quality of economic evaluations of non-drug therapies? A systematic review and critical appraisal of economic evaluations of radiotherapy for cancer.

E-pub date: 31 Oct 2014


Radiogenomics: radiobiology enters the era of big data and team science.

E-pub date: 15 Jul 2014


A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.

E-pub date: 31 May 2014


Patient reported outcome measures (PROMs) following forward planned field-in field IMRT: results from the Cambridge Breast IMRT trial.

E-pub date: 31 May 2014


The Cambridge post-mastectomy radiotherapy (C-PMRT) index: a practical tool for patient selection.

E-pub date: 31 Mar 2014


Randomized controlled trial of intensity-modulated radiotherapy for early breast cancer: 5-year results confirm superior overall cosmesis.

E-pub date: 20 Dec 2013


Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.

E-pub date: 01 Oct 2013


Normal tissue complication probability (NTCP) parameters for breast fibrosis: pooled results from two randomised trials.

E-pub date: 31 Aug 2013


Intensity-modulated Radiotherapy for the Treatment of Breast Cancer.

E-pub date: 31 Mar 2013


Optimization and comparison of balloon-based partial breast brachytherapy using a single source, a standard plan line source, and both forward and inverse planned multilumen techniques.

E-pub date: 31 Mar 2013


Tumour bed delineation for partial breast/breast boost radiotherapy: what is the optimal number of implanted markers?

E-pub date: 01 Feb 2013


Current controversies in breast cancer: do we have the answers?

E-pub date: 01 Feb 2013


Breast radiotherapy: less is more?

E-pub date: 01 Feb 2013


Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity.

E-pub date: 31 Dec 2012


Does participation in clinical trials influence the implementation of new techniques? A look at changing techniques in breast radiotherapy in the UK.

E-pub date: 31 Oct 2012


Association of breast tumour bed seroma with post-operative complications and late normal tissue toxicity: results from the Cambridge Breast IMRT trial.

E-pub date: 31 Oct 2012


A replicated association between polymorphisms near TNFα and risk for adverse reactions to radiotherapy.

E-pub date: 07 Aug 2012


Relationship between irradiated breast volume and late normal tissue complications: a systematic review.

E-pub date: 31 Jul 2012


Radiotherapy research trials in the UK: secrets of success.

E-pub date: 31 May 2012


How does imaging frequency and soft tissue motion affect the PTV margin size in partial breast and boost radiotherapy?

E-pub date: 31 May 2012


Standardized Total Average Toxicity score: a scale- and grade-independent measure of late radiotherapy toxicity to facilitate pooling of data from different studies.

E-pub date: 01 Mar 2012


Randomized controlled trial of forward-planned intensity modulated radiotherapy for early breast cancer: interim results at 2 years.

E-pub date: 01 Feb 2012


Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study.

E-pub date: 31 Jan 2012


The Cambridge Breast Intensity-modulated Radiotherapy Trial: patient- and treatment-related factors that influence late toxicity.

E-pub date: 31 Dec 2011


Evaluation of implanted gold seeds for breast radiotherapy planning and on treatment verification: a feasibility study on behalf of the IMPORT trialists.

E-pub date: 31 Aug 2011


Lifelong learning in clinical oncology editorial series: introduction and overview.

E-pub date: 01 Jun 2011


Planning with intensity-modulated radiotherapy and tomotherapy to modulate dose across breast to reflect recurrence risk (IMPORT High trial).

E-pub date: 15 Mar 2011


Hypofractionated whole-breast radiotherapy for women with early breast cancer: myths and realities.

E-pub date: 01 Jan 2011


No association between SNPs regulating TGF-β1 secretion and late radiotherapy toxicity to the breast: results from the RAPPER study.

E-pub date: 31 Oct 2010


Establishment of a Radiogenomics Consortium.

E-pub date: 01 Apr 2010


Target volume definition for external beam partial breast radiotherapy: clinical, pathological and technical studies informing current approaches.

E-pub date: 31 Mar 2010


Localising the tumour bed in breast radiotherapy.

E-pub date: 01 Feb 2010


A randomised controlled trial of forward-planned radiotherapy (IMRT) for early breast cancer: baseline characteristics and dosimetry results.

E-pub date: 31 Jul 2009


Titanium clip placement to allow accurate tumour bed localisation following breast conserving surgery: audit on behalf of the IMPORT Trial Management Group.

E-pub date: 01 Jun 2009


Clinical impact of computed tomography-based image-guided brachytherapy for cervix cancer using the tandem-ring applicator – the Addenbrooke’s experience.

E-pub date: 01 Apr 2009


Characterization of target volume changes during breast radiotherapy using implanted fiducial markers and portal imaging.

E-pub date: 01 Mar 2009


Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype.

E-pub date: 01 Feb 2009


Concurrent weekly cisplatin chemotherapy and radiotherapy in a haemodialysis patient with locally advanced cervix cancer.

E-pub date: 01 Feb 2008


Breast cancers: noninvasive method of preoperative localization with three-dimensional US and surface contour mapping.

E-pub date: 01 Nov 2007


Early radiotherapy dose response and lack of hypersensitivity effect in normal brain tissue: a sequential dynamic susceptibility imaging study of cerebral perfusion.

E-pub date: 31 Oct 2007


High definition three-dimensional ultrasound to localise the tumour bed: a breast radiotherapy planning study.

E-pub date: 01 Sep 2007


Radiosensitivity, Radiogenomics & RAPPER.

E-pub date: 01 Apr 2007


The IMPORT trials are launched (September 2006).

E-pub date: 01 Oct 2006


Reduction of radiotherapy-induced late complications in early breast cancer: the role of intensity-modulated radiation therapy and partial breast irradiation. Part II–Radiotherapy strategies to reduce radiation-induced late effects.

E-pub date: 01 Apr 2005


Reduction of radiotherapy-induced late complications in early breast cancer: the role of intensity-modulated radiation therapy and partial breast irradiation. Part I–normal tissue complications.

E-pub date: 01 Feb 2005


Quantitative assessment of inter-clinician variability of target volume delineation for medulloblastoma: quality assurance for the SIOP PNET 4 trial protocol.

E-pub date: 01 Nov 2003


Avascular necrosis in patients treated with BEP chemotherapy for testicular tumours.

E-pub date: 01 Aug 2000


Hyperbaric oxygen therapy. Combination with radiotherapy in cancer is of proved benefit but rarely used.

E-pub date: 31 Mar 1999


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