Visiting scientist

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Work address: 
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE

Measurement of plasma cell-free mitochondrial tumor DNA improves detection of glioblastoma in patient-derived orthotopic xenograft models.

E-pub date: 31 Oct 2018

Enhanced detection of circulating tumor DNA by fragment size analysis.

E-pub date: 31 Oct 2018

Using prognosis to guide early detection and treatment selection in non-metastatic prostate cancer.

E-pub date: 31 Oct 2018

Classification and Personalized Prognosis in Myeloproliferative Neoplasms.

E-pub date: 30 Sep 2018

A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer.

E-pub date: 31 Aug 2018

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.

E-pub date: 31 May 2018

The role of TET-mediated DNA hydroxymethylation in prostate cancer.

E-pub date: 15 Feb 2018

Determination of complex subclonal structures of hematological malignancies by multiplexed genotyping of blood progenitor colonies.

E-pub date: 31 Jan 2018

Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data.

E-pub date: 01 Sep 2017

Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer.

E-pub date: 29 Aug 2017

Implementing liquid biopsies into clinical decision making for cancer immunotherapy.

E-pub date: 18 Jul 2017

Association Of Plasma And Urinary Mutant DNA With Clinical Outcomes In Muscle Invasive Bladder Cancer.

E-pub date: 17 Jul 2017

CVE: an R package for interactive variant prioritisation in precision oncology.

E-pub date: 25 May 2017

Liquid biopsies come of age: towards implementation of circulating tumour DNA.

E-pub date: 01 Apr 2017

Corrigendum to “Integration of Copy Number and Transcriptomics Provides Risk Stratification in Prostate Cancer: A Discovery and Validation Cohort Study” [EBioMedicine 2 (9) (2015) 1133-1144].

E-pub date: 31 Mar 2017

The importance of DNA methylation in prostate cancer development.

E-pub date: 01 Feb 2017

HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer.

E-pub date: 15 Nov 2016

Whole blood mRNA in prostate cancer reveals a four-gene androgen regulated panel.

E-pub date: 31 Oct 2016

The Early Effects of Rapid Androgen Deprivation on Human Prostate Cancer.

E-pub date: 31 Aug 2016

Methods to Identify Chromatin-Bound Protein Complexes: From Genome-Wide to Locus-Specific Approaches.

E-pub date: 31 Aug 2016

Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target.

E-pub date: 31 May 2016

Kinase joins the chaperone club: Androgen-regulated kinome reveals choline kinase alpha as a potential drug target in prostate cancer.

E-pub date: 31 May 2016

STAT1 activation in association with JAK2 exon 12 mutations.

E-pub date: 31 Jan 2016

DNMT3A mutations occur early or late in patients with myeloproliferative neoplasms and mutation order influences phenotype.

E-pub date: 01 Nov 2015

Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study.

E-pub date: 01 Sep 2015

A glycolytic phenotype is associated with prostate cancer progression and aggressiveness: a role for monocarboxylate transporters as metabolic targets for therapy.

E-pub date: 31 Aug 2015

Epigenetic and oncogenic regulation of SLC16A7 (MCT2) results in protein over-expression, impacting on signalling and cellular phenotypes in prostate cancer.

E-pub date: 28 Aug 2015

Corrigendum: analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.

E-pub date: 01 Jun 2015

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells.

E-pub date: 01 Jun 2015

The evolutionary history of lethal metastatic prostate cancer.

E-pub date: 16 Apr 2015

HES5 silencing is an early and recurrent change in prostate tumourigenesis.

E-pub date: 01 Apr 2015

Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.

E-pub date: 01 Apr 2015

Effect of mutation order on myeloproliferative neoplasms.

E-pub date: 12 Feb 2015

Nongenetic stochastic expansion of JAK2V617F-homozygous subclones in polycythemia vera?

E-pub date: 20 Nov 2014

N-acetyl-L-aspartyl-L-glutamate peptidase-like 2 is overexpressed in cancer and promotes a pro-migratory and pro-metastatic phenotype.

E-pub date: 06 Nov 2014

JAK2V617F promotes replication fork stalling with disease-restricted impairment of the intra-S checkpoint response.

E-pub date: 21 Oct 2014

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer.

E-pub date: 01 Oct 2014

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.

E-pub date: 01 Aug 2014

Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer.

E-pub date: 17 Jun 2014

The ETS family member GABPα modulates androgen receptor signalling and mediates an aggressive phenotype in prostate cancer.

E-pub date: 01 Jun 2014

HES6 drives a critical AR transcriptional programme to induce castration-resistant prostate cancer through activation of an E2F1-mediated cell cycle network.

E-pub date: 31 May 2014

The transcriptional programme of the androgen receptor (AR) in prostate cancer.

E-pub date: 31 Mar 2014

Inactivating CUX1 mutations promote tumorigenesis.

E-pub date: 31 Jan 2014

Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2.

E-pub date: 19 Dec 2013

Peroxiredoxin-3 is overexpressed in prostate cancer and promotes cancer cell survival by protecting cells from oxidative stress.

E-pub date: 20 Aug 2013

The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man.

E-pub date: 14 Jan 2013

Mapping protein-DNA interactions using ChIP-sequencing.

E-pub date: 31 Aug 2012

Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts.

E-pub date: 13 Oct 2011

Global identification of androgen response elements.

E-pub date: 31 Aug 2011

The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis.

E-pub date: 20 May 2011

Cooperative interaction between retinoic acid receptor-alpha and estrogen receptor in breast cancer.

E-pub date: 15 Jan 2010

Chromatin immunoprecipitation (ChIP) methodology and readouts.

E-pub date: 31 Aug 2009

Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer.

E-pub date: 22 Jul 2008

Pro-neural transcription factors as cancer markers.

E-pub date: 19 May 2008

ChIPping away at gene regulation.

E-pub date: 01 Apr 2008

The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel.

E-pub date: 31 Dec 2007

New androgen receptor genomic targets show an interaction with the ETS1 transcription factor.

E-pub date: 01 Sep 2007

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