Research Assistant

Research Group Home Page: 

Work address: 
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE

Mapping and elucidating the function of modified bases in DNA

E-pub date: 01 Sep 2017

Base resolution maps reveal the importance of 5-hydroxymethylcytosine in a human glioblastoma.

E-pub date: 31 Aug 2017

Enhanced Methylation Analysis by Recovery of Unsequenceable Fragments.

E-pub date: 31 Aug 2016

In vivo genome-wide profiling reveals a tissue-specific role for 5-formylcytosine.

E-pub date: 29 Jun 2016

Chemical methods for decoding cytosine modifications in DNA.

E-pub date: 25 Mar 2015

5-Formylcytosine alters the structure of the DNA double helix.

E-pub date: 31 Jan 2015

The biology and genomic localization of cytosine modifications

E-pub date: 31 Dec 2014

Chemical biology of genomic DNA: minimizing PCR bias.

E-pub date: 18 Oct 2014

A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation.

E-pub date: 31 Aug 2013

Selective RNA versus DNA G-quadruplex targeting by in situ click chemistry.

E-pub date: 29 Oct 2012

Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase.

E-pub date: 17 Aug 2012

A non-canonical DNA structure is a binding motif for the transcription factor SP1 in vitro.

E-pub date: 01 Feb 2012

Differential requirement for cathepsin D for processing of the full length and C-terminal fragment of the malaria antigen MSP1.

E-pub date: 31 Aug 2011

Control of olefin geometry in macrocyclic ring-closing metathesis using a removable silyl group.

E-pub date: 22 Jun 2011

An expedient synthesis of orthogonally protected lysinoalanine from Aloc-protected Garner’s aldehyde

E-pub date: 30 Nov 2010

Targeted delivery of antigen processing inhibitors to antigen presenting cells via mannose receptors.

E-pub date: 21 May 2010

Stabilized integrin-targeting ternary LPD (lipopolyplex) vectors for gene delivery designed to disassemble within the target cell.

E-pub date: 18 Mar 2009

New stabilising groups for lateral lithiation of ortho-cresol derivatives and a new route to 2-substituted chromans

E-pub date: 31 May 2008

Novel heparin/heparan sulfate mimics as inhibitors of HGF/SF-induced MET activation.

E-pub date: 15 Nov 2007

New stabilising groups for lateral lithiation of ortho-cresol derivatives

E-pub date: 31 Aug 2007

Synthesis of 5-aza-analogues of angucyclines: manipulation of the 2-deoxy-C-glycoside subunit

E-pub date: 31 Oct 2005

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