Research Fellow

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Work address: 
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE

Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups.

E-pub date: 28 Feb 2019

Global transcriptional analysis identifies a novel role for SOX4 in tumor-induced angiogenesis.

E-pub date: 30 Nov 2018

A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation.

E-pub date: 30 Sep 2018

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.

E-pub date: 31 Aug 2018

SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis.

E-pub date: 31 Jul 2018

MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models.

E-pub date: 31 Jul 2018

High USP6NL Levels in Breast Cancer Sustain Chronic AKT Phosphorylation and GLUT1 Stability Fueling Aerobic Glycolysis.

E-pub date: 01 Jul 2018

RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer.

E-pub date: 01 May 2018

Computational approach to discriminate human and mouse sequences in patient-derived tumour xenografts.

E-pub date: 05 Jan 2018

PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models.

E-pub date: 01 Nov 2017

BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity.

E-pub date: 01 Oct 2017

Interrogating open issues in cancer medicine with patient-derived xenografts.

E-pub date: 31 Aug 2017

Intersect-then-combine approach: improving the performance of somatic variant calling in whole exome sequencing data using multiple aligners and callers.

E-pub date: 18 Apr 2017

Interrogating open issues in cancer precision medicine with patient-derived xenografts.

E-pub date: 01 Apr 2017

Tumor heterogeneity

E-pub date: 31 Dec 2016

Patient-derived tumour xenografts for breast cancer drug discovery.

E-pub date: 31 Dec 2016

Lack of RAD51 foci formation enables the identification of PARP inhibitor sensitive breast tumors

E-pub date: 01 Dec 2016

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.

E-pub date: 22 Sep 2016

Modeling Breast Cancer Intertumor and Intratumor Heterogeneity Using Xenografts.

E-pub date: 31 Aug 2016

PARP1/2 inhibition in a subset of triple negative breast cancer (TNBC) patient-derived tumor xenografts (PDX) identifies predictive biomarkers of response

E-pub date: 31 Jan 2016

PARP inhibition in breast and ovarian patient-derived tumor xenografts (PDX) harboring germline BRCA1/2 mutations unveils mechanisms of primary and acquired resistance that restore homologous recombination (HR)

E-pub date: 31 Jan 2016

Context-Specific Effects of TGF-β/SMAD3 in Cancer Are Modulated by the Epigenome.

E-pub date: 22 Dec 2015

Corrigendum: Progesterone receptor modulates ERα action in breast cancer.

E-pub date: 01 Oct 2015

Maintaining Tumor Heterogeneity in Patient-Derived Tumor Xenografts.

E-pub date: 01 Aug 2015

Progesterone receptor modulates ERα action in breast cancer.

E-pub date: 16 Jul 2015

Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution.

E-pub date: 19 Feb 2015

The EurOPDX consortium: Sharing patient tumor-derived xenografts for collaborative multicentric preclinical trials.

E-pub date: 01 Nov 2013

A copy number and expression based classifier for breast cancer tumors

E-pub date: 01 Oct 2013

TGFβ induces the formation of tumour-initiating cells in claudinlow breast cancer.

E-pub date: 31 Aug 2012

ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium.

E-pub date: 31 Mar 2011

High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene.

E-pub date: 01 Feb 2007

Glucocorticoid receptor-JNK interaction mediates inhibition of the JNK pathway by glucocorticoids.

E-pub date: 31 Oct 2003

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