Research Associate

Research Group Home Page: 
Marioni Group

Work address: 
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way Cambridge CB2 0RE

EmptyDrops: distinguishing cells from empty droplets in droplet-based single-cell RNA sequencing data.

E-pub date: 28 Feb 2019

Transcriptional Heterogeneity in Naive and Primed Human Pluripotent Stem Cells at Single-Cell Resolution.

E-pub date: 31 Dec 2018

Transcription-factor-mediated supervision of global genome architecture maintains B cell identity.

E-pub date: 01 Nov 2018

COMRADES determines in vivo RNA structures and interactions.

E-pub date: 31 Aug 2018

T cell cytolytic capacity is independent of initial stimulation strength.

E-pub date: 31 Aug 2018

Detection and removal of barcode swapping in single-cell RNA-seq data.

E-pub date: 10 Jul 2018

Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors.

E-pub date: 01 Jun 2018

Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis.

E-pub date: 01 Jun 2018

Genome-wide analysis reveals no evidence of trans chromosomal regulation of mammalian immune development.

E-pub date: 01 Jun 2018

beachmat: A Bioconductor C++ API for accessing high-throughput biological data from a variety of R matrix types.

E-pub date: 31 May 2018

iSEE: Interactive SummarizedExperiment Explorer.

E-pub date: 01 Jan 2018

Isolation and Comparative Transcriptome Analysis of Human Fetal and iPSC-Derived Cone Photoreceptor Cells.

E-pub date: 12 Dec 2017

Assessing the reliability of spike-in normalization for analyses of single-cell RNA sequencing data.

E-pub date: 01 Nov 2017

Testing for differential abundance in mass cytometry data.

E-pub date: 31 Jul 2017

Overcoming confounding plate effects in differential expression analyses of single-cell RNA-seq data.

E-pub date: 01 Jul 2017

No counts, no variance: allowing for loss of degrees of freedom when assessing biological variability from RNA-seq data.

E-pub date: 25 Apr 2017

Scater: pre-processing, quality control, normalization and visualization of single-cell RNA-seq data in R.

E-pub date: 15 Apr 2017

A non-canonical function of Ezh2 preserves immune homeostasis.

E-pub date: 01 Apr 2017

Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity.

E-pub date: 20 Sep 2016

A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor.

E-pub date: 31 Aug 2016

From reads to genes to pathways: differential expression analysis of RNA-Seq experiments using Rsubread and the edgeR quasi-likelihood pipeline.

E-pub date: 31 Aug 2016

Infrastructure for genomic interactions: Bioconductor classes for Hi-C, ChIA-PET and related experiments.

E-pub date: 31 Aug 2016

It’s DE-licious: A Recipe for Differential Expression Analyses of RNA-seq Experiments Using Quasi-Likelihood Methods in edgeR.

E-pub date: 31 Aug 2016

Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations.

E-pub date: 01 Jun 2016

Pooling across cells to normalize single-cell RNA sequencing data with many zero counts.

E-pub date: 27 Apr 2016

RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity.

E-pub date: 26 Apr 2016

csaw: a Bioconductor package for differential binding analysis of ChIP-seq data using sliding windows.

E-pub date: 18 Mar 2016

Transcriptome and H3K27 tri-methylation profiling of Ezh2-deficient lung epithelium.

E-pub date: 01 Sep 2015

From reads to regions: a Bioconductor workflow to detect differential binding in ChIP-seq data.

E-pub date: 31 Aug 2015

diffHic: a Bioconductor package to detect differential genomic interactions in Hi-C data.

E-pub date: 19 Aug 2015

[Eagle’s syndrome].

E-pub date: 31 May 2015

Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung.

E-pub date: 15 Apr 2015

EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival.

E-pub date: 01 Apr 2015

De novo detection of differentially bound regions for ChIP-seq data using peaks and windows: controlling error rates correctly.

E-pub date: 01 Jun 2014

Polycomb repressive complex 2 (PRC2) suppresses Eμ-myc lymphoma.

E-pub date: 10 Oct 2013

Mass trees: a new phylogenetic approach and algorithm to chart evolutionary history with mass spectrometry.

E-pub date: 04 Jun 2013

FluShuffle and FluResort: new algorithms to identify reassorted strains of the influenza virus by mass spectrometry.

E-pub date: 20 Aug 2012

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