Dr Zena Werb received her B.Sc. in Biochemistry from the University of Toronto, and her Ph.D. in Cell Biology from Rockefeller University, New York. After postdoctoral studies at the Strangeways Research Laboratory in Cambridge England, she was recruited to the University of California San Francisco faculty, where she is currently Professor of Anatomy and Associate Director for Basic Science, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco. Dr. Werb is recognized internationally for her fundamental discoveries about the role of matrix metalloproteinases, the cellular microenvironment and intercellular communication in the normal functioning and pathogenesis of tissues, in particular, breast cancer. She has published over 450 papers. Her honors include a Guggenheim Fellowship, the E. B. Wilson Medal, American Society for Cell Biology and election to the National Academy of Sciences, the National Academy of Medicine, and the American Academy of Arts and Sciences.